Browsing University of Galway Theses (PhD Theses) by Subject "Desmosomes"
Now showing items 1-3 of 3
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Analysis of the role of Rho GTPases in epithelial cells
(2014-11-19)Rho GTPases are a family of small GTP binding proteins that function as molecular switches for the control of a variety of fundamental cellular processes, and therefore represent potentially vital proteins for skin ... -
Characterization of a novel zebrafish model of arrhythmogenic right ventricular cardiomyopathy
(NUI Galway, 2018-12-14)Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) is a congenital heart disorder characterized by replacement of the ventricular myocardium with fibrofatty tissue. The majority of cases are due to mutations in genes ... -
Desmosomal armadillo proteins in zebrafish cardiac development
(2012-12-18)Plakoglobin and plakophilin-2 are desmosomal armadillo proteins, required for correct cardiac development in zebrafish. Mutations in the human genes can cause the congenital heart defect arrhythmogenic right ventricular ...