Browsing University of Galway Theses (PhD Theses) by Author "Boyd, Aoife"
Now showing items 1-7 of 7
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The effects of Vibrio parahaemolyticus on Mitogen Activated Protein Kinase signalling pathways and intestinal epithelial host cell responses
Finn, Rebecca (2013-02-20)Vibrio parahaemolyticus is a gram negative bacterium that is found in marine and estuarine environments. Although found amongst the commensal flora of shellfish, V. parahaemolyticus is a potent human pathogen. Consumption ... -
Functional screening of human faecal microbiome metagenome library for glycoside hydrolase enzymes
Mulualem, Daniel (NUI Galway, 2020-04-24)Members of the human gut microbiota use glycoside hydrolase (GH) enzymes, such as sialidases, α-fucosidases and β-galactosidases to forage on host mucin glycans and dietary fibers. A human faecal metagenomic library was ... -
Identification and characterisation of novel glycan-binding bacterial adhesins encoded by the human gut microbial metagenome
Agbavwe, Christy (2017-03-24)Although there have been an increasing number of scientific publications describing the adherence of gut bacteria to components of the human intestinal mucosa, very little is known about the surface molecules mediating ... -
Investigation of pathogenic vibrio in Irish aquaculture
Boyle, Katie Louise (NUI Galway, 2023-07-31)Vibrio parahaemolyticus, Vibrio vulnificus and Vibrio cholerae are marine pathogens that cause gastroenteritis in humans after the consumption of infected shellfish. Vibrio can cause devastating losses of oysters, shrimps ... -
The molecular mechanisms governing the colonisation of intestinal epithelial cells by Vibrio parahaemolyticus
O Boyle, Nicholas (2012-12-19)Vibrio parahaemolyticus is a food borne gastro-intestinal pathogen of major global importance. The organism induces severe inflammatory diarrhea in individuals who become infected due to the consumption of contaminated ... -
Stress response and virulence of Vibrio vulnificus: role of the stressosome and secondary effects of antibiotic resistance
Cutugno, Laura (NUI Galway, 2021-12-22)Bacterial stress response and virulence are two key factors that guarantee the survival and propagation of pathogens. The elucidation of factors that affect these aspects in the human pathogen Vibrio vulnificus was the ... -
Virulence mechanisms as targets for biodiscovery in combatting antimicrobial resistance: Identification and characterization of antibacterial and anti-virulence molecules from marine sponges and snake venom
Khan, Neyaz (NUI Galway, 2022-06-14)Emergence and spread of antimicrobial resistanceposes a serious health concern.Using conventional antibiotics will speed upthis process because of the selective pressure it confers to the bacteria. ...