Browsing University of Galway Theses (PhD Theses) by Subject "Actin cytoskeleton"
Now showing items 1-3 of 3
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Experimental and computational investigation of the active force generation of cells subjected to static and dynamic loading
(2016-05-13)The development of a mechanistic understanding of the processes by which cells sense and actively respond to the mechanical environment would represent a significant advance in the fields of biomechanics and tissue ... -
The Response of Cells to the Mechanical Environment: A Numerical Investigation of the Actin Cytoskeleton and Cell Adhesion
(2012-10-21)Numerous in-vitro studies have established that cells possess the ability to sense and react to their physical environment. However, the mechanisms underlying such mechanotransduction are poorly understood. Previous cell ... -
The Role of the Actin Cytoskeleton in the Response of Chondrocytes to Mechanical Loading: A Computational and Experimental Investigation
(2012-09-28)The biomechanisms which govern the response of chondrocytes to mechanical stimuli are poorly understood. This thesis aims to provide a more in depth understanding of chondrocyte biomechanics by focusing on the role of actin ...