Browsing University of Galway Theses (PhD Theses) by Subject "cognition"
Now showing items 1-4 of 4
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Assessment of the consequences of gestational SSRI antidepressant exposure in the rat
(NUI Galway, 2019-10-08)Although the most common psychotropic drugs prescribed in pregnancy are selective serotonin reuptake inhibitor (SSRI) antidepressants, their health impact on the resultant offspring is largely unknown due to the ethical ... -
Post-genome-wide association study investigations of the polygenic basis of schizophrenia and cognition
(NUI Galway, 2022-10-14)Schizophrenia (SCZ) is a chronic, severe mental disorder affecting approximately 1% of the population worldwide. A core feature of SCZ is cognitive dysfunction in the form of impairments in memory, attention and IQ. Both ... -
The role of the endogenous opioid system in hyperalgesia associated with negative affect
(NUI Galway, 2020-02-26)Pain and negative affect (anxiety and depression) modulate one another reciprocally. However, the neurobiological mechanisms underlying this interaction are unclear. The endogenous opioid system plays a key role in regulating ... -
The role of the endogenous opioid system in social motivation and cognition in the valproic acid model of social impairment
(NUI Galway, 2019-11-11)Positive social interactions and successful relationships are important for physical and mental health, and have been shown to elicit beneficial effects on multiple physiological systems and bodily function. Impairments ...