Browsing University of Galway Theses (PhD Theses) by Subject "DNA"
Now showing items 1-4 of 4
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DNA hybridisation detection on chemically modified electrodes with bioelectrocatalytic amplification of signal
(2011-12-22)Electrochemical detection of DNA hybridization is a viable alternative to optical and radio-labelled techniques. The benefits of using biosensors based on electrochemical systems are: high sensitivity, possible development ... -
Impacts of DNA damage on the pericentriolar material and centriole duplication
(2015-12-03)The centrosome consists of two barrel-shaped centrioles embedded in a proteinaceous pericentriolar material (PCM), a highly organised scaffold that serves as a platform for proteins that regulate spindle assembly, protein ... -
Inhibition of polyomavirus DNA replication by nucleotide analogs
(2017-01-31)Polyomaviruses are non-evenloped circular DNA viruses that cause severe polyomavirus-associated diseases in immune compromised individuals. The diseases associated with these viruses have been on the rise due to myriad of ... -
Synthesis and investigation of artificial metallonucleases
(2015-04-29)The aim of this work is the synthesis and investigation of artificial metallonucleases. In the first part of this work a simple model system was used allowing for the quantification of the artificial nucleases ability. ...