Browsing University of Galway Theses (PhD Theses) by Author "Donohoe, Gary"
Now showing items 1-6 of 6
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Cognitive functioning in schizophrenia: Characterising the effects of common genetic variation, brain structure, inflammation, and early life adversity
Corley, Emma (NUI Galway, 2024-03-08)Schizophrenia is a complex, highly polygenic neuropsychiatric disorder. Individuals with schizophrenia experience neurocognitive and social cognitive deficits that can impact their ability to work, live independently, ... -
Cognitive remediation and social recovery in early psychosis (THE CReSt-R STUDY)
Frawley, Emma (NUI Galway, 2023-05-11)Background Psychosis, even in its early stages, is associated with significant disability, causing it to be ranked ahead of paraplegia and blindness in those aged 18–35 in terms of years lived with disability. Current ... -
Early life adversities and social cognition in schizophrenia
Rokita, Karolina Izabela (NUI Galway, 2020-09-02)Childhood adversity constitutes a major public health problem as it leads to numerous negative physical and mental consequences in later life. In individuals with schizophrenia, the prevalence of early life adversities ... -
The impact of childhood trauma on structural brain connectivity in schizophrenia: A diffusion MRI and network based study
Costello, Laura (NUI Galway, 2021-12-29)Schizophrenia is a severe and heterogeneous neuropsychiatric disorder affecting approximately 1% of the world’s population. In recent years, exposure to childhood trauma has been established as a prominent environmental ... -
Neurocognitive effects of risk factors for psychosis: Neuropsychological and neuroimaging studies of immune-related genetic and environmental factors
Holland, Jessica (NUI Galway, 2020-04-16)Schizophrenia (SZ) is a debilitating psychiatric disorder that afflicts approximately 1% of people worldwide. It is often characterized by hallucinations, sometimes by emotional blunting, and in a majority of cases by a ... -
Neurocognitive effects of risk variants for psychosis: neuropsychological and neuroimaging studies of variants and pathways
Cosgrove, Donna (2017-07-19)Schizophrenia is a complex, highly polygenic brain disorder. Cognitive deficits in schizophrenia are among the most disabling symptoms, and as of yet, have no effective treatment. Investigating the effect of genetic variants ...