Browsing University of Galway Theses (PhD Theses) by Author "Alkermes Inc"
Now showing items 1-2 of 2
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Exploration of the opioidergic system in the olfactory bulbectomized rat model of depression
McHugh, Kelly Louise (NUI Galway, 2020-02-27)In recent years, there has been renewed interest in targeting the central opioid system as a novel strategy for the treatment of psychiatric disorders such as depression, due to its involvement in the regulation of mood, ... -
The role of the endogenous opioid system in hyperalgesia associated with negative affect
Ferdousi, Mehnaz (NUI Galway, 2020-02-26)Pain and negative affect (anxiety and depression) modulate one another reciprocally. However, the neurobiological mechanisms underlying this interaction are unclear. The endogenous opioid system plays a key role in regulating ...