Browsing University of Galway Theses (PhD Theses) by Title
Now showing items 554-573 of 2242
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Discovery and characterization of novel poriferan biosynthetic pathways via next-generation sequencing
(NUI Galway, 2023-01-10)Sponges of the phylum Porifera are benthic, filter feeding animals which can be found in waters throughout the world. Because of these qualities, consistent challenges they face include exposure to ... -
Discrete vector fields and the cohomology of certain arithmetic and crystallographic groups
(2015-05-26)This thesis has two main topics: Arithmetic groups and Crystallographic groups. The work on arithmetic groups SL(2, Z[1/m]) was motivated by a question of Kevin Hutchinson and also a generalization of the paper "On the ... -
Discursive representations and translation practice: the constructed reader of Irish literature in Italian
(2013-05-31)This thesis approaches translation as a transformative act, which involves the decontextualisation of the source text and its recontextualisation within the target language culture. For literary works, the attempt to make ... -
Displacement and relocation in early modern Ireland: Studies of transplantation settlement in Connacht and Clare
(2012-10-26)This thesis is a study of three diverse Catholic families that received land during the mid seventeenth-century Cromwellian transplantation to and within Connacht and Clare. Transplantees, while being united in their ... -
Disruption of NEDD8 protein conjugation as a novel therapy for acute myeloid leukemia
(2012-08-15)The coordinated balance between the synthesis and degradation of proteins is an important regulator of cancer cell biology. The ubiquitin-proteasome system (UPS) is responsible for the timed destruction of many proteins ... -
Dissecting the evolution of resistance to microtubule hyper-stabilization
(NUI Galway, 2024-01-31)When microtubules are hyper-stabilized, they do not provide the proper tension at the kinetochore of the metaphase chromosomes. Low tension leads to the activation of the spindle assembly checkpoint which stops cells ... -
Dissecting the monster: mapping discourses of medicine, ethics, and monstrosity in the Victorian Penny Blood
(2017-02-02)This research analyses a set of specimens of penny blood literature from the point of view of medical history, with the goal of providing an examination of the genre in relation to its historical context. In so doing, it ... -
Dissecting the pan-placodal gene regulatory network reveals novel interactions driving sense organ development in vertebrates
(2016-02-17)The genes encoding the transcription factor Six1, and its co-factor Eya1 together mark the embryonic territory - the pan-placodal ectoderm (PPE) - that gives rise to most cranial sense organs in vertebrates. Mutation of ... -
Distinct mechanisms underlie oral versus aboral regeneration in the cnidarian hydractinia echinata
(2014-10-24)Distinct mechanisms underlie oral versus aboral regeneration in Hydractinia echinata. Head regeneration is preceded by stem cell migration, proliferation and blastema formation. After decapitation stem cells migrate from ... -
Distributed dataflow processing of large RDF graphs
(2017-05-29)As part of the big data world, RDF, the graph-based data model of the Semantic Web, is growing in use. Consequently, the size of available RDF data is increasing and massive datasets are becoming commonplace. Nevertheless, ... -
Diversion: A comparative study of law and policy relating to defendants and offenders with mental health problems and intellectual disability
(2013-11-29)This thesis examines law and policy relating to defendants and offenders with mental health problems and intellectual disability. It is a comparative study of diversion in Ireland, England and Wales, Northern Ireland, ... -
Diversity, species concepts and phylogenetic relationships of some marine algae in a perspective of Biodiscovery
(2013-06-06)The overall goal was to investigate the genetic diversity, phylogenetic relationships and taxonomy of some groups of marine algae of particular interest from a taxonomic and biogeographic point of view in a perspective of ... -
DNA hybridisation detection on chemically modified electrodes with bioelectrocatalytic amplification of signal
(2011-12-22)Electrochemical detection of DNA hybridization is a viable alternative to optical and radio-labelled techniques. The benefits of using biosensors based on electrochemical systems are: high sensitivity, possible development ... -
DNA mediated chromatin pull-down: a novel method for the study of chromatin replication
(2012-04-27)Chromatin replication involves duplicating DNA while maintaining epigenetic information. These processes are critical for genome stability and for preserving cell-type identity. To investigate how these processes are ... -
DNA methylation and zygotic genome activation during early embryogenesis of animals
(NUI Galway, 2020-10-25)Upon fertilization, after the fusion of two pronuclei, the newly formed zygotic genome is transcriptionally inactive. Hence, early animal development is driven by maternal RNAs and proteins. The zygotic genome becomes ... -
Doing justice to gender diversity: Narratives of progress and the limits of law
(NUI Galway, 2020-06-22)The core question of my doctoral thesis asks what is meant by the recognition of gender in law, and what effects the emergence of a multiplicity of gender identities onto international human rights law forums has had on ... -
Domain adaptive extraction of topical hierarchies for Expertise Mining
(2013-09-11)In this age of pervasive internet access we have become accustomed to rely on web search for our most basic information needs. But complex queries in knowledge-intensive organisations, as well as in the academic environment, ... -
Dominant discourse and prevailing practice: positioning financial education within education
(2016-07-06)In the last decade of the 20th century, Ireland experienced a period of unprecedented growth in the economy, being dubbed ‘the Celtic Tiger’(Smith). Parallel to this came about significant societal shifts, as a new ... -
Doppeltes spiel: Selbstreflexive konfigurationsstrategien als gegenstand einer kritischen textpraxis digitaler spiele. Analysen und interpretationen zu Vagrant Story, Dark Souls III und Horizon: Zero Dawn
(NUI Galway, 2020-05-07)Seen as a comparatively recent phenomenon, digital games continue to challenge academic discourse. The study argues that digital games are best understood as both complex configurational practices as well as audio-visually ... -
Drámaíocht ó dhúchas? Stáitsiú na nealaíon béil san fhichiú haois
(2013-06-04)Déantar iniúchadh sa tráchtas seo ar chur i láthair na n-ealaíon béil san fhichiú haois. Dhá ardán atá i gceist nuair a thagraítear do 'stáitsiú na n-ealaíon béil' sa teideal, mar atá, stáitse na gcomórtas agus stáitse na ...