Browsing University of Galway Theses (PhD Theses) by Title
Now showing items 469-488 of 2242
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Development and application of molecular tools for the study of farmed and wild Atlantic cod (Gadus morhua) stocks
(2016-05-31)Atlantic cod (Gadus morhua) is a commercially and ecologically important fish inhabiting the shelf areas of the North Atlantic. Several genetic resources were developed for the study of cod in this thesis. Fifty-five new ... -
Development and applications of optical imaging techniques for microcirculation and cardiovascular imaging
(2016-08-12)The work presented in this thesis describes the development and applications of optical imaging techniques, optical coherence tomography (OCT) and photoacoustic (PA) imaging, for the purpose of diagnosing and treating ... -
Development and characterisation of a novel preclinical test battery for detecting anxiolytic and antidepressant properties of drugs
(2016-10-19)Depression is a chronic, recurring and potentially life-threatening disorder that is highly comorbid with anxiety. The aetiology of depression, anxiety and their comorbidity is still largely unknown. Despite the development ... -
Development and characterisation of a novel, anatomically relevant rat model of acute postoperative pain
(2014-09-30)Acute postoperative pain remains a significant healthcare issue, delaying discharge and prolonging convalescence periods, resulting in high social and economic costs. Depending on the type of surgical procedure performed, ... -
Development and characterisation of compressed, macro-porous and collagen-coated poly-ε-caprolactone electrospun meshes
(NUI Galway, 2019-02-25)Electrospun scaffolds are utilised in a diverse spectrum of clinical targets, with an ever-increasing quantity of work progressing to clinical studies and commercialisation. However, the very dense architecture and the low ... -
Development and characterisation of novel gene-environment interaction rat models of Parkinson's disease
(2016-08-04)Despite its discovery almost 60 years ago, levodopa remains the most effective therapy for the treatment of the motor symptoms associated with Parkinson’s disease. However, chronic use of levodopa is associated with serious ... -
Development and characterisation of recognition molecules for the specific identification of non-human glycans
(2015-01-26)Glycosylation is an enzymatic process through which glycans attach to proteins, lipids and other organic molecules with huge structural diversity. This is a common post-translational modification found on proteins and cell ... -
Development and evaluation of an assessment tool for identification of elements of situation awareness in OSCEs in undergraduate medical curricula
(NUI Galway, 2018-07-20)Situation awareness (SA) is recognised as an important factor in patient safety and clinical decision making in conjunction with diagnostic and therapeutic reasoning. Missed diagnosis and treatment errors have been identified ... -
Development and evaluation of an online hypnosis programme for the treatment of migraine
(NUI Galway, 2018-10-17)This study examined the development and evaluation of an online hypnosis programme for the treatment of migraine. 43 participants who suffered with two or more migraines a month and who satisfied other study criteria ... -
Development and evaluation of an online version of the Feeling Better pain management programme for children and their care-givers
(NUI Galway, 2019-10-08)Abstract Background: Reasons for poor management of paediatric chronic pain include lack of access to psychological support for pain management. Research evidence is increasingly focused on online interventions as a ... -
Development and evaluation of platform-based SERS substrates for detecting cancer biomarkers at ultra-low concentrations
(2017-04-27)Surface Enhanced Raman Scattering (SERS) has proved to be a powerful spectroscopic tool since its discovery in 1973. Advances in nanofabrication techniques increasingly allow for the manufacture of complex nanostructured ... -
Development and Implementation of an Ultra High Speed Astronomical Polarimeter: The Galway Astronomical Stokes Polarimeter (GASP)
(2013-05-12)Optical polarization is a powerful diagnostic tool in astrophysics, allowing the investigation of asymmetries in source regions of astronomical objects, magnetic field configurations, and magnetic field strengths. Polarized ... -
Development and optimisation of an oxygen-based amendment for cattle slurry designed to reduce methane emissions during storage
(NUI Galway, 2023-11-07)Methane (CH4) is a potent greenhouse gas (GHG) that is produced via anaerobic digestion in slurry storage facilities, which are ubiquitous in farming systems with animal husbandry. Globally, CH4 emissions from agriculture ... -
Development and Psychometric Evaluation of a Scale to Assess Sexual Difficulties in Gay Men
(2013-12-20)A sexual difficulty or dysfunction has been defined as the disturbance or inadequacy of normal sexual responding (Rowland, 2007). The Diagnostic and Statistical Manual for Mental Disorders (DSM-5; American Psychiatric ... -
Development and testing of behaviour change based intervention for machine related safety on farms
(NUI Galway, 2024-04-15)Background Farm machinery-related injuries are a growing concern worldwide, posing serious risks to farmers' safety and leading to severe disabilities or fatalities. As the farming population ages and farming machinery ... -
The development and validation of a measure assessing gender role conflict in male adolescents
(2014-01-08)The purpose of these studies was to develop a psychometrically sound questionnaire that addresses outstanding empirical issues in adolescent gender role conflict and, in so doing, enhance understanding of the negative ... -
Development of 3D breast cancer model to study extracellular vesicle crosstalk
(NUI Galway, 2024-01-31)3D model systems are crucial in establishing novel therapeutics and understanding cell interactions in the tumor microenvironment. Extracellular vesicles (EVs) are promising carriers of therapeutic cargo for tumor-targeted ... -
Development of a Chemical Kinetic Mechanism for Small Hydrocarbons
(2014-01-07)A detailed chemical kinetic mechanism has been developed to describe the oxidation of small hydrocarbon and oxygenated hydrocarbon species. In order to understand the oxidation of large hydrocarbon and oxygenated hydrocarbon ... -
The Development of a Computational Test-Bed to Assess Coronary Stent Implantation
(2013-03-15)The implantation behaviour of coronary stents is of great interest to clinicians and engineers alike as in-stent restenosis (ISR) remains a critical issue with the community. ISR is hypothesized to occur for ... -
The development of a digital intervention to promote timely presentation of breast cancer symptoms to a healthcare professional
(NUI Galway, 2019-10-31)Breast cancer is the primary cause of death among women globally and in Ireland, mortality rates from breast cancer are the third highest in Europe. Early diagnosis of breast cancer is linked to more favourable outcomes ...