Browsing University of Galway Theses (PhD Theses) by Title
Now showing items 423-442 of 2242
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Depth of field reduction for miniature-camera imaging
(NUI Galway, 2020-08-25)This thesis investigates the reduction of depth-of- field for miniature camera systems, such as the ones embedded in smartphones. The work on digital shallow depth-of- field is already mature and implemented in most modern ... -
Derivative Estimation in Noisy Data; an Additive Penalty P-Spline Approach
(2010-12-20)In many situations it is of primary interest to estimate the rate of change of the relationship between response and explanatory variables. In this thesis derivative estimation using spline smoothing is explored. A review ... -
Describing the indescribable: Lexical obscurity and biblical exegesis in early medieval Ireland
(NUI Galway, 2022-06-27)In the seventh century, medieval Irish scholars, who had received and internalised an educational system that placed the Bible at its very centre, began to produce texts that were marked by innovation in artistic style and ... -
Design and development of a performance evaluation framework for remote eye gaze estimation systems
(NUI Galway, 2019-04-02)In this dissertation, a comprehensive evaluation framework for remote eye gaze estimation systems that are implemented in consumer electronics applications is developed. For this, firstly, a detailed literature review ... -
Design and development of polymeric transfection vectors for gene delivery in Recessive Dystrophic Epidermolysis Bullosa
(2014-07-23)Recessive Dystrophic Epidermolysis Bullosa (RDEB) is caused by mutations in the collagen VII gene (COL7A1) that lead to an alteration of function or a reduction in the amounts of collagen VII protein (C7). Any of these ... -
Design and development of smart contract system for blockchain based applications
(NUI Galway, 2021-05-17)The work presented in this thesis describes the design and development of smart contract system for blockchain based applications. The main objective is to investigate the current state of blockchain technology and its ... -
Design and evaluation of an automated algorithm for cardiac risk stratification
(2013-12-20)In the United States, sudden cardiac death (SCD) claims approximately 450,000 lives each year, more lives than stroke, lung and breast cancer and AIDS combined. In the United Kingdom and Ireland, the combined figure is ... -
The Design and Evaluation of Graphical Radial Menus
(2011-12-05)Graphical menus provide slow performance and yet users often try to select menu commands as fast as possible. Shortcut techniques that enable users to by-pass selections from a graphical menu are fast, but are not the ... -
Design and synthesis of biocompatible metal-organic frameworks for anti-cancer, anti-tubercular and MRI application
(NUI Galway, 2023-07-11)Metal-organic frameworks (MOFs) are relatively new porous materials that have attracted significant attention in recent decades. Potential applications in gas storage and separation have been at the forefront of this ... -
Design and synthesis of macrocycles, peptides and coiled coils with sugar connections
(2016-06-09)Migrastatin is a secondary metabolite that is formed from the bacterium Streptomyces platensis. This compound has shown promising anti-metastatic activity by inhibiting tumour cell migration. Published derivatives of this ... -
Design and synthesis of novel constrained glycomimetics as inhibitors of galectins and galactosidases
(NUI Galway, 2023-10-10)Chapter 1 gives a brief introduction to carbohydrate structure, discussing factors influencing reactivity and conformation, such as the anomeric and exo-anomeric effect. Chapter 1 mentions methods of structural analysis ... -
Design Exploration of EMBRACE Hardware Spiking Neural Network Architecture and Applications
(2014-02-05)The operation and structure of the human brain has inspired the development of next generation smart embedded computing systems. The cognitive abilities of the human brain have been partially explained by the dense and ... -
Design of fibre-reinforced polymer composite blades for wind and tidal turbines
(2017-09)There is substantial opportunity in the development of wind and tidal current turbines to help decarbonise national energy systems and to expand the economic potential of the European Union. However, well-documented cases ... -
Design thinking capability model: A management framework to support design thinking implementation for product development
(NUI Galway, 2019-10-08)Design thinking is lauded to reduce cost and redesign work in the new product development process and shorten lead time to development. Because of that, researchers are investigating how to use using design thinking as ... -
Design, analysis and testing of a spiral blade vertical-axis tidal turbine
(NUI Galway, 2021-05-04)The aim of this thesis is to develop a combined analytical, computational and experimental methodology for characterisation and optimisation of the hydrodynamic performance of a novel vertical-axis tidal turbine concept. ... -
Design, development and validation of a series of multiplex real-time PCR diagnostics assays for the rapid and accurate detection and differentiation of the Mycobacterium tuberculosis complex
(2012-03-01)Tuberculosis (TB) remains a major health concern both in developed and developing countries due to the high rates of morbidity and mortality associated with disease. In humans, TB is caused by members of the Mycobacterium ... -
The Design, Development and Validation of a Wearable Behaviour Monitor for the Autonomous Assessment of the Functional Health of Older Adults
(2013-12-23)Functional ability describes a person's capability to perform those tasks that are necessary to live independently. It is a proven predictor of functional decline, the need for hospitalisation and institutionalisation ... -
The design, manufacture and testing of a composite polysialic acid mimetic peptide loaded collagen nerve graft for use in peripheral nerve repair
(NUI Galway, 2016-02-15)Peripheral nerve injuries can be debilitating for patients. The current gold-standard technique for peripheral nerve repair is autograft. This procedure involves harvesting a non-critical nerve from a donor site from the ... -
Design, synthesis and catalytic activity of novel oxazoline based ligands
(2015-08-14)This thesis can be viewed as two separate studies. Firstly, the design, synthesis and catalytic activity of novel 2-pyridyl mono(oxazoline). A family of mono(oxazoline) ligands were developed in which the 5-poition is ... -
Design, synthesis and evaluation of glycomimetics as galectin inhibitors
(NUI Galway, 2024-03-11)Chapter-1: This chapter begins with a short review on carbohydrates and their structure and then summarises some highlights from the last two decades of research on developing carbohydrate-based drug candidates. Included ...