Browsing University of Galway Theses (PhD Theses) by Title
Now showing items 399-418 of 2245
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Current and potential diagnostic modalities in the detection and management of breast cancer
(NUI Galway, 2021-07-06)Global statistics have demonstrated that breast cancer is the most frequently diagnosed cancer and the leading cause of cancer death among female patients, accounting for 23 percent of total cancer cases and 14 percent of ... -
Cycling and transport of phosphorus and nitrogen from harvested peatland forests and possible mitigation and methods
(2012-11-16)Drainage of peatlands has been part of forestry practice since the early 20th century. In Ireland and the UK, approximately 800,000 ha of peat catchments were drained and afforested between the 1950s and 1990s. A large ... -
Cycloaddition reactions of imidazolium and phthalazinium dicyanomethanide 1,3-dipoles: synthesis, mechanism and the effect of water
(2017-09-28)The cycloaddition reactions of imidazolium-3-dicyanomethanide 1,3-dipoles with electron poor alkene and alkyne dipolarophiles were explored. The reactions of these azolium 1,3-dipoles with alkyne dipolarophiles generated ... -
Cytotoxic drug induced JNK activation is DR5-dependent and vital for apoptosis and provides a new target for MSC-mediated delivery of DR5-specific sTRAIL variants
(2013-03-20)Over the past two decades, cancer research has produced tremendous advances in our understanding of the pathogenesis of cancer. Among the most important of these advances is the realization that apoptosis and the proteins ... -
Dairy and grassland economics in an era of possible expansion
(2015-10-14)Thesis focuses on the efficiency and the Total Factor Productivity (TFP) which is associated with the dairy enterprise of Specialist Dairy farms. The approach uses econometric methods to generate its measures. Special ... -
Damage and permeability in linerless composite cryogenic tanks
(2015-09-29)Carbon fibre reinforced polymers (CFRP) are one of the prospective material families being investigated for use in the fuel tanks of future reusable launch vehicles (RLVs). The extreme cryogenic thermo-mechanical loading ... -
The dark side of humanity: psychopathy, psychiatry and human nature
(2017-10-11)Psychopathy or antisocial personality disorder is generally conceived as a neurophysiological disorder undermining moral reasoning or sentiment, leading to behaviour which contravenes social and moral norms. This psychiatric ... -
Dashboards for supporting cancer care in value-based healthcare context – Information needs, design principles and acceptance
(NUI Galway, 2021-09-19)Improving the value of care is central to the value-based healthcare model. This model emphasises the active role of patients in decision making and providing them with the information they require during the different ... -
Data availability analysis in P2P networks
(2012-09-28)P2P network architectures have gained popularity as applications for sharing files between users. A P2P network provides a scalable, robust, and economical storage architecture. These features have led to the extended ... -
The Death Penalty in Africa
(2011-09-29)This study begins by addressing the issue of the death penalty in Africa prior to foreign legal influences. An Africanist view exhorts retentionist countries to repeal the death penalty simply because it is an imperialist ... -
Deciphering anaerobic ethanol oxidation for better recovery of renewable energy from wastewater
(NUI Galway, 2024-03-28)Anaerobic digestion is a promising technology relying on complex microbial interactions to convert organics into methane, achieving sustainable energy recovery. Ethanol is an important low-molecular intermediate during ... -
Deciphering the geomorphic and sedimentary record of the last Irish Ice Sheet in NW Donegal, Ireland: implications for glacial dynamics and decay configurations
(2012-04-13)The last Irish Ice Sheet has a long history of investigation, but its characteristics and behaviour remain elusive. A comprehensive reconstruction of the last Irish Ice Sheet of NW Donegal is presented in this thesis. It ... -
Deciphering the role of human MSL2 and MSL1 within and beyond the MSL complex
(2018-01-14)While the components of the MSL (Male Specific Lethal) complex in Drosophila are well studied and known to play a critical role in dosage compensation, there is little known about the function of its evolutionary conserved ... -
Decoding the kinematic and ionisation structure of axisymmetric nebulae
(NUI Galway, 2021-08-04)The aim of the thesis was to develop a code and pipeline for generating 3D photoionisation models of axisymmetric nebulae to better understand their ob- served structure and composition. This was achieved through a new ... -
Deconstructing the man, constructing the saint: the literary sanctification of Germanus of Auxerre in the "Vita Germani Auctore Constantio" by Constantius of Lyon
(2013-09-27)The narrative structure of the Vita Germani Auctore Constantio is based on its protagonist's spiritual development from man to saint. In the early chapters, Germanus' character is defined by human actions and attitudes, ... -
Deconstructing the man, constructing the saint: the literary sanctification of germanus of Auxerre in the vita germani auctore constantio
(2013-09-30)The narrative structure of the Vita Germani Auctore Constantio is based on its protagonist's spiritual development from man to saint. In the early chapters, Germanus' character is defined by human actions and attitudes, ... -
The decoration of the litterae notabiliores in the Cathach of Columcille
(NUI Galway, 2019-09-02)The aim of this study is to examine the litterae notabiliores of what is known as the Cathach of Colum Cille (RIA MS. 12 R 33), the manuscript of a fragment of a psalter said to have been written in the late sixth century ... -
Decoy Receptors block tumour cell eradication by TRAIL - Molecular engineering of TRAIL to evade decoy receptors
(2012-06-29)Tumour necrosis factor-related apoptosis inducing ligand (TRAIL) is a cytokine expressed by immune cells which selectively eradicates a wide range of cancer cells while leaving normal healthy cells unharmed. TRAIL binds ... -
Deep learning techniques in data augmentation and neural network design
(NUI Galway, 2020-05-22)In recent years, deep learning has revolutionized computer vision and has been applied to a range of problems where it often achieves accuracies equal to or greater than those obtainable by individual human experts. This ... -
Deep-retrofit decision-making support for achieving nearly zero-energy buildings with enhanced comfort
(NUI Galway, 2019-04-11)The emerging trends for deep-retrofit of existing buildings in Europe require formulation of strategies for nearly zero-energy buildings (nZEBs) and achieving benchmarks as outlined in the Energy Performance of Buildings ...