Browsing University of Galway Theses by Subject "Zebrafish"
Now showing items 1-4 of 4
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Characterization of a novel zebrafish model of arrhythmogenic right ventricular cardiomyopathy
(NUI Galway, 2018-12-14)Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) is a congenital heart disorder characterized by replacement of the ventricular myocardium with fibrofatty tissue. The majority of cases are due to mutations in genes ... -
Desmosomal armadillo proteins in zebrafish cardiac development
(2012-12-18)Plakoglobin and plakophilin-2 are desmosomal armadillo proteins, required for correct cardiac development in zebrafish. Mutations in the human genes can cause the congenital heart defect arrhythmogenic right ventricular ... -
The Influence of Environmental Estrogens on Early-life Stage Zebrafish Development
(2013-03-27)Endocrine disrupting compounds (EDCs) including bisphenol A (BPA) and genistein may induce estrogenic effects in organisms. Genistein is a naturally occurring plant compound found mainly in soy products while BPA is used ... -
A role for nanor in early zebrafish development and validation of a neurotoxic zebrafish model of Parkinson’s disease
(NUI Galway, 2018-04-06)Zebrafish are a versatile experimental model which have progressed the fields of many research areas through both genetic and pharmacological studies. In this thesis I studied a novel zygotic gene, nanor, in zebrafish and ...