Browsing University of Galway Theses by Author "O'Byrne, Conor"
Now showing items 1-7 of 7
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The development of reporters to measure the general stress response in Listeria monocytogenes: population and single cell studies on the activation of SigmaB
Utratna, Marta (2012-09-28)The foodborne pathogen Listeria monocytogenes has a remarkable ability to persist and grow in harsh environments, including the human gastrointestinal tract. This attribute is regulated, at least partly, by the alternative ... -
Elucidation of the role of the glutamate decarboxylase system and the gamma-aminobutyric acid shunt pathway in the stress response of Listeria monocytogenes
Feehily, Conor (2014-07-22)The foodborne pathogen Listeria monocytogenes is the causative agent of listeriosis in humans and other animals. This disease can have a fatality rate of up to 30% in infected patients and leads to spontaneous abortion in ... -
Identification and characterisation of novel glycan-binding bacterial adhesins encoded by the human gut microbial metagenome
Agbavwe, Christy (2017-03-24)Although there have been an increasing number of scientific publications describing the adherence of gut bacteria to components of the human intestinal mucosa, very little is known about the surface molecules mediating ... -
Investigation into the prevalence and persistence of Listeria monocytogenes in Irish seafood: Possible roles for σB in environmental persistence
NicAogáin, Kerrie (2017-03-31)L. monocytogenes is a robust bacterial pathogen capable of surviving in a wide range of environments including food processing facilities. This pathogen is of concern for the food processing industry particularly producers ... -
Molecular investigation into the roles of Sigma B and the Stressosome in the response of Listeria monocytogenes to environmental stress
Dorey, Amber Louise (NUI Galway, 2019-07-15)The alternative sigma factor, SigB, has been studied extensively in Listeria monocytogenes, Bacillus subtilis and Staphylococcus aureus, and is known to regulate the general stress response in these bacteria. The activation ... -
Overlaps in the regulatory networks of Listeria monocytogenes in response to environmental cues
Marinho, Catarina (NUI Galway, 2019-09-30)The facultative intracellular pathogen Listeria monocytogenes is a highly adaptable organism widely distributed in the environment. The ingestion of food contaminated with L. monocytogenes by at-risk individuals can ... -
Understanding the role of the general stress response regulator, RpoS, in the environmental persistence of Escherichia coli
Somorin, Yinka (2017-04-03)The use of E. coli as an indicator organism for faecal contamination in the environment, particularly in water sources, is based partly on the assumption that E. coli survives transiently outside of the mammalian ...