Browsing University of Galway Theses by Subject "Cornea"
Now showing items 1-3 of 3
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Ex vivo generation of bone marrow derived regulatory dendritic cells for promotion of corneal allograft survival.
(2013-09-27)Investigations into cell based therapies for application in organ transplantation has grown significantly. Here, I describe the ex vivo generation of donor bone marrow derived dendritic cells (BMDCs) and examine the ... -
Ex-vivo generation of regulatory T-cells expressing transcription factor foxp3 and their application in cornea transplantation
(2011-05-27)This project investigated the therapeutic potential of allo-antigen specific regulatory T-cells in the context of penetrating keratoplasty. Two methods of ex-vivo generation of T regulatory cells have been explored in ... -
Novel gene therapeutic approaches to prolong corneal allograft survival
(2012-09-28)Cornea transplantation (penetrating keratoplasty) is the most frequent form of allograft transplantation in humans with a 90 % success rate in the first 2 years, however, the rate of survival decreases over time and drops ...