Browsing University of Galway Theses by Subject "adrenal"
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The role of the liver X receptor in mitotane therapy in adrenocortical carcinoma
(NUI Galway, 2020-08-12)Adrenocortical carcinoma (ACC) is a rare, aggressive malignancy with limited treatment options. The Liver X Receptor α (LXRα) is highly expressed in the adrenal cortex, and functions to regulate cholesterol and lipid ...