Browsing University of Galway Theses by Subject "DGCR8"
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The microprocessing factor DGCR8 interacts with ATM and functions independently of its partner DROSHA in the DDR
(NUI Galway, 2020-01-23)The eukaryotic cell has evolved a complex suite of mechanisms called the DNA damage response (DDR), that acts by sensing DNA damage and reacting appropriately to maintain genomic integrity. The PIK kinase ATM is a key ...