Browsing University of Galway Theses by Author "Crowley, Peter"
Now showing items 1-5 of 5
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Biosupramolecular protein tectonics
Ramberg, Kiefer (NUI Galway, 2021-03-31)Taking a structural biology approach, this thesis describes in-depth investigations into protein bioconjugation (PEGylation), surface recognition (synthetic receptors), and ligand-mediated assembly (crystalline frameworks). ... -
Calixarene-mediated protein assembly
McGovern, Róise Ella (2014-05-23)Solved the first crystal structure of a protein-calixarene complex (at 1.4 Angstrom resolution). The results provide exact structural information on the amino acid preference of the anionic p-sulfonatocalix[4]arene (sclx4) ... -
Polyhedric features of cysteine: from protein functionalization to copper-binding
Cattani, Giada (2015-03-30)This thesis comprises two main projects which are about the cysteine chemistry involved in protein functionalization and copperbinding. Plastocyanin functionalization via cysteine has been used to produce a conjugate ... -
Protein-carbohydrate interactions and structural characterization of Ralstonia solanacearum lectin
Antonik, Pawel (2017-03-20)Ralstonia solanacearum is a bacterium which causes fatal damage to hundreds of agricultural plants such as potato or tobacco. It produces two lectins that are involved in attachment of the bacterium to the host. One of ... -
Supramolecular ‘Glues’ for protein recognition and assembly
Alex, Jimi (NUI Galway, 2019-12-06)Supramolecules such as calixarenes, cucurbiturils and foldamers are rapidly emerging as tools for protein assembly. This thesis builds on past successes with some of these scaffolds. Previously, sulfonato-calix[4]arene was ...