Browsing University of Galway Theses by Author "Biggs, Manus"
Now showing items 1-6 of 6
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Fabrication of biomimetic electrodes by laser processing and two photon lithography
Kelly, Adriona (NUI Galway, 2020-06-07)The brain machine interface BMI describes a group of technologies capable of communicating with excitable nervous tissue within the central nervous system (CNS). BMI’s have seen major advances in recent years, but these ... -
A multimodal neuromodulation approach to nervous tissue repair and regeneration
Britton, James (NUI Galway, 2022-01-06)Regeneration of damaged nervous tissue is one of the remaining frontiers for bioengineers. Nerve tissue injuries have devastating consequences and carry substantial economic and social implications. For example, the annual ... -
Physicochemical and biological functionalisation strategies of the neuroelectrode interface to promote neural integration through the modulation of reactive gliosis
Vallejo Giraldo, Catalina (2017-12-05)Implanted neuroprosthetics and neuroelectrode systems have been under investigation for a number of decades and have been proven to be safe and efficacious as treatments for several neurological disorders including ... -
Piezoelectric scaffolds: Mediating tendon regeneration by activation of piezosensitive receptors
Fernandez, Marc (NUI Galway, 2019-09-15)Tendon disease caused by trauma, illness or age-related degeneration constitutes an unmet clinical need. Tendon repair using different pharmacological and engineering strategies based on both synthetic and biological grafts ... -
Replicating and modulating skin fibrosis in vitro: Multi-compartment collagen devices as dual drug delivery vehicles
Coentro, João (NUI Galway, 2022-01-10)Complex pathologies, such as fibrosis, are often not the result of a singular event, but rather the consequence of multiple disruptions in the normal balance between intricately connected organs, tissues and signalling ... -
Three-layer collagen-based composite scaffolds to spatially direct tissue-specific cell differentiation for enthesis repair
Pugliese, Eugenia (NUI Galway, 2023-09-28)The enthesis is a specialised interfacial tissue responsible to minimise stress concentrations between tendon and bone. Fibrocartilaginous entheses are composed of four distinct areas, namely tendon, unmineralised ...