Browsing University of Galway Theses by Title
Now showing items 553-572 of 2275
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Development of transgenic and genome editing tools to study the role of Notch signalling in Hydractinia echinata
(2016)Hydractinia is a colony forming marine invertebrate and a member of the phylum Cnidaria. Members of this genus have been models for developmental biologists for over a century and feature many characters of evolutionary ... -
The Development of Ultra Wideband Scanning Techniques for Detection and Classification of Breast Cancer
(2010-09-30)This thesis addresses the development of imaging techniques for the early detection of breast cancer, based on Ultra Wideband (UWB) radar, a promising emerging technology that exploits the dielectric contrast between normal ... -
The development, implementation, and evaluation of a theory-based concussion education programme for secondary school Gaelic Athletic Association (GAA) athletes
(NUI Galway, 2018-05)Sport-related concussion (SRC) is a public health concern (Thurman, Branche, & Sniezek, 1998), especially among children and adolescent athletes, as their brains are still developing (Field, Collins, Lovell & Marron, 2003; ... -
Developments in health literacy over time: A longitudinal qualitative research study
(NUI Galway, 2019-12-12)Introduction Conceptualising health literacy as a relational concept, which involves how individuals interact with complex health and social systems, requires a greater understanding of the context of people’s health ... -
Diagnostic insights from twenty years of bilateral inferior petrosal sinus sampling for Cushings Disease at Mayo Clinic (1998-2018)
(NUI Galway, 2020-03-02)Pituitary-dependent Cushing syndrome (CS), referred to herein as Cushing Disease (CD), is the most common cause of endogenous CS. The challenge for diagnosing CD includes difficulty identifying the often small pituitary ... -
Dialectical dividends: fostering hybridity of new pedagogical practices and partnerships in science education and outreach
(2015-09-02)Internationally, science literacy has become socially and economically very important. Many European countries, including Ireland, stress that science and technology graduates are fundamental for economic growth. Nevertheless, ... -
Diet and renal outcomes
(2014-11)Chronic Kidney Disease (defined by decreased glomerular filtration rate and proteinuria) is associated with significant morbidity, increased cardiovascular risk and premature mortality. Advanced chronic kidney disease, ... -
Differences in immunogenicity between cancer mutation signatures shed light on immunoediting
(NUI Galway, 2024-04-15)Immunoediting is a process through which the immune system plays a role in shaping the mutational landscape of cancer and, consequently, in cancer progression. One critical aspect of immunoediting is the phenomenon known ... -
Differentiated thyroid cancer – Evaluation of contemporary management and novel risk assessment
(NUI Galway, 2021-07-08)Introduction Differentiated thyroid cancer (DTC) is a heterogeneous disease with a spectrum of phenotypes ranging from indolent to aggressive variants. The incidence of DTC has increased by 300% over the past 15 years ... -
The diffusion of global human resource information technology in the subsidiaries of a US multinational corporation
(2011-08-26)The majority of multinational corporations (MNC) utilise some form of global human resource information technology (GHRIT) to collect, store and analyse employee data. The literature suggests that the use of GHRIT has the ... -
Diffusion-based models for semantic relatedness
(NUI Galway, 2020-05-14)The assessment of semantic relatedness for a given pair of entities in a knowledge graph has become a critical step in a wide variety of artificial intelligence tasks, including but not restricted to fields such as machine ... -
Digital ensemble: exploring the design of technology-enhanced learning to mobilise and augment students' engagement with English literature
(2015-06-24)Students are disengaging from learning and literature learning in post primary education in Ireland due to an over-emphasis on rote learning practices and the constraints of high stakes, summative assessments (Chief ... -
Digital youth building digital capacity: The experience of rural communities in Manitoba, Canada
(NUI Galway, 2020-08-31)Today's digital society creates new realities and opportunities for rural communities. To fully take advantage of those digital opportunities, rural communities must build the capacity and culture to utilize digital ... -
Dihedral codes
(2009)In this thesis we give new constructions of a number of extremal type II codes. Algebraic proofs are provided that the constructions do in fact yield the codes. The codes are constructed using group rings of which the ... -
Disability, deficiency and excess: a critical re-examination of the construction, production and representations of physical disability in contemporary European film
(2014-06-26)This thesis critically investigates three contemporary European disability films to examine how representation and metaphor are used to present physical disability as deficient in comparison with the able-bodied ideal. The ... -
Discovery and characterization of novel poriferan biosynthetic pathways via next-generation sequencing
(NUI Galway, 2023-01-10)Sponges of the phylum Porifera are benthic, filter feeding animals which can be found in waters throughout the world. Because of these qualities, consistent challenges they face include exposure to ... -
Discrete vector fields and the cohomology of certain arithmetic and crystallographic groups
(2015-05-26)This thesis has two main topics: Arithmetic groups and Crystallographic groups. The work on arithmetic groups SL(2, Z[1/m]) was motivated by a question of Kevin Hutchinson and also a generalization of the paper "On the ... -
Discursive representations and translation practice: the constructed reader of Irish literature in Italian
(2013-05-31)This thesis approaches translation as a transformative act, which involves the decontextualisation of the source text and its recontextualisation within the target language culture. For literary works, the attempt to make ... -
Displacement and relocation in early modern Ireland: Studies of transplantation settlement in Connacht and Clare
(2012-10-26)This thesis is a study of three diverse Catholic families that received land during the mid seventeenth-century Cromwellian transplantation to and within Connacht and Clare. Transplantees, while being united in their ... -
Disruption of NEDD8 protein conjugation as a novel therapy for acute myeloid leukemia
(2012-08-15)The coordinated balance between the synthesis and degradation of proteins is an important regulator of cancer cell biology. The ubiquitin-proteasome system (UPS) is responsible for the timed destruction of many proteins ...