Browsing University of Galway Theses by Title
Now showing items 325-344 of 2236
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A computational and experimental investigation of the in-vivo biomechanics of the human aorta
(NUI Galway, 2020-07-06)The overall objective of this thesis is to provide a new understanding of the degree of biomechanical heterogeneity that exists along the human aorta, against the backdrop of clinical literature reporting that patient ... -
A computational and experimental investigation of tracheobronchial stent performance
(2017-05-25)Tracheobronchial stents are used to relieve blockages in the respiratory tree, typically caused by lung cancer. However, multiple complications can be associated with stents for this indication. In order to be able to ... -
Computational design of glycomimetic inhibitors of Influenza A Adhesion
(2015-02-16)Many pathogens, such as avian influenza, Helicobacter pylori and Streptococcus pneumoniae, employ cell-surface glycans which terminate in Neu5AcAlpha(2-3)Gal as their adhesion partner.[1] As a result, a glycomimetic ... -
Computational development of a particle-In-cell computer code for the simulation of plasma Instabilities around rotation powered pulsars
(2014-09-03)This thesis reports on the design and development of DYMPHNA3D, a 3D particle-in-cell (PIC) plasma simulation code. It also focuses on the field of radio emission and the discovery of rotation powered neutron stars, ... -
Computational Homology of Cubical and Permutahedral Complexes
(2012-09-28)Homology is the study of connectivity and "holes" in spaces. The aim of this thesis is to introduce and develop a theory of permutahedral complexes for computations of homology of large data sets and to compare, using ... -
Computational homology of n-types
(2014-01-10)An n-type X is a CW-space with homotopy groups \pi_iX=0 for all i>n. Up to homotopy equivalence such a space can be specified algebraically by means of a simplicial group whose Moore complex is trivial in degrees >= n. For ... -
A computational investigation of the laser bonding of balloon catheters
(2015-09-28)The balloon catheters produced by Boston Scientific are manufactured using a laser bonding process. The behaviour of the materials during this laser welding process is not very well understood. In this work a computational ... -
A computational investigation of the long-term performance of bioabsorbable magnesium-based implants in orthopaedic fracture applications
(NUI Galway, 2023-06-20)Current orthopaedic fixation devices made from stainless steel and titanium can lead to a range of long-term complications that include bone reabsorption due to stress shielding, implant loosening and/or infection. ... -
Computational methods for micromechanics characterisation: Application to and experimental investigation of metal additive manufacturing and heat treatment processes
(NUI Galway, 2022-11-23)Powder bed fusion (PBF) is an additive manufacturing process in which finely focused thermal energy is used to selectively melt target regions within thin layers of metal powders. Due to the complex thermal conditions ... -
Computational modelling framework for predicting the evolution of biodegradable polymers during degradation
(NUI Galway, 2022-11-28)Biodegradable polymers are attractive alternatives for many permanent implants, potentially reducing long term risks. Designing optimal devices for their intended purpose, however, is costly and time consuming, with small ... -
Computational modelling of emissions from gas turbines: Ensuring experimental reliability and quantifying emissions uncertainty
(NUI Galway, 2019-02-18)Global environmental concerns and the increasing amount of power generated using gas turbines have led to the development of dry low emission (DLE) combustion systems to minimize the NOx and CO pollutants. Improvements in ... -
Computational modelling of linear friction welding of Inconel 718
(NUI Galway, 2022-07-15)Linear friction welding (LFW) is a solid-state joining technique that involves the rapid reciprocating motion of two workpieces under large compressive pressure, in order to generate friction heat and plastically deformed ... -
Computational modelling of the coupled electro-mechanical behaviour of neurons
(NUI Galway, 2019-01-22)Recent experimental evidence has uncovered complex biophysical phenomena accompanying the electrical activity of nervous cells. Now emerging theories refer to the electric pulse, i.e. the Action Potential (AP), as an ... -
Computational modelling of the degradation of poly-L-lactide for a bioresorbable polymeric stent
(NUI Galway, 2020-05-08)The interest in biodegradable polymers for the design of bioresorbable stents, temporary vascular scaffolds designed to restore patency to obstructed vessels, has witnessed a dramatic growth over the last ten to fifteen ... -
Computational modelling of thermofluid flashing in MSF desalination
(2017-08-21)Phase change inside a desalination flashing chamber arises from the surface evaporation with self-boiling of liquid brine flow due to a reduction of pressure. Flashing flow is the key to desalination of the feed water in ... -
Computational Studies of Hypericin and Porphyrin Derivatives for Photodynamic Therapy - Spectra, Membrane Simulations, and Protein Interactions
(2011-08)Photosensitizing compounds with potential application in anticancer treatment with photodynamic therapy were investigated by means of computational methods in the studies presented in this thesis. Hypericin and brominated ... -
Computationally Guided Directed Evolution of O-GlcNAcase into a Reagent Specific for [beta]-O-GlcNAc
(2013-12-13)Protein glycosylation with O-linked N-Acetylglucosamine (O-GlcNAc) is a post-translational modification of serine and threonine residues in nucleocytoplasmic proteins. Alterations in the glycosylation pattern of O-GlcNAc ... -
Computing invariants of knotted manifolds
(NUI Galway, 2022-09-13)In this thesis, we develop algorithms in computational topology for working with regular CW-complexes and calculating associated homological invariants. We adapt the classical notion of broken surface diagrams for describing ... -
Conceiving Unity of Being: The Environmental Modernism of R. M. Rilke and W. B. Yeats
(2013-09-30)This thesis explores the works of two of the most influential European modernists, Rainer Maria Rilke and William Butler Yeats, in the light of the relatively recent formation of the theoretical paradigm of eco-criticism. ... -
A conceptual history of the idea of self-causation: from Plato's forms to Hegel's concrete universal
(2015-09-29)The dissertation is a historical-cum-conceptual examination of the idea of self-causation (causa sui). In the Western metaphysical tradition, self-causation has been understood in two ways: (i.) as an individual existent’s ...