Browsing College of Science by Subject "DNA"
Now showing items 1-4 of 4
-
Determination of the number of RAD51 molecules in different human cell lines
(Taylor & Francis, 2019-11-15)Knowledge about precise numbers of specific molecules is necessary for understanding and verification of biological pathways. The RAD51 protein is central in the repair of DNA double-strand breaks (DSBs) by homologous ... -
Investigation of non-covalent interactions of metal complexes with DNA in cell-free systems
(Schweizerische Chemische Gesellschaft, 2017-03-01)Non-covalent interactions of metallo compounds with DNA range from the simple, unspecific electrostatic binding of a positively charged metal complex to the sequence-selective recognition of DNA binding sites due to shape, ... -
Phosphate diester cleavage, DNA interaction and cytotoxic Activity of a bimetallic bis(1,4,7-triazacyclononane) zinc complex
(Wiley, 2014-06-24)The dinuclear zinc complex [Zn-2{bcmp(-H)}(mu-Cl)](ClO4)(2)center dot H2O {bcmp = 2,6-bis(1,4,7-triazacyclonon-1-ylmethyl)-4-methylphenol} has been synthesized and structurally characterized. The DNA binding affinity was ... -
Rapid unwinding of triplet repeat hairpins by Srs2 helicase of Saccharomyces cerevisiae
(2008)Expansions of trinucleotide repeats cause at least 15 heritable human diseases. Single-stranded triplet repeat DNA in vitro forms stable hairpins in a sequence-dependent manner that correlates with expansion risk in vivo. ...