Browsing College of Science by Subject "COMPLEX"

Now showing items 1-4 of 4

    • Cell cycle-dependent mobility of Cdc45 determined in vivo by fluorescence correlation spectroscopy 

      Broderick, Ronan; Ramadurai, Sivaramakrishnan; Tóth, Katalin; Togashi, Denisio M.; Ryder, Alan G.; Langowski, Jörg; Nasheuer, Heinz-Peter (Public Library of Science, 2012-04-19)
      Eukaryotic DNA replication is a dynamic process requiring the co-operation of specific replication proteins. We measured the mobility of eGFP-Cdc45 by Fluorescence Correlation Spectroscopy (FCS) in vivo in asynchronous ...

    • Cognitive analysis of schizophrenia risk genes that function as epigenetic regulators of gene expression 

      Whitton, Laura; Cosgrove, Donna; Clarkson, Christopher; Harold, Denise; Kendall, Kimberley; Richards, Alex; Mantripragada, Kiran; Owen, Michael J.; O'Donovan, Michael C.; Walters, James; Hartmann, Annette; Konte, Betina; Rujescu, Dan; Gill, Michael; Corvin, Aiden; Rea, Stephen; Donohoe, Gary; Morris, Derek W. (Wiley, 2016-10-20)
      Epigenetic mechanisms are an important heritable and dynamic means of regulating various genomic functions, including gene expression, to orchestrate brain development, adult neurogenesis, and synaptic plasticity. These ...

    • Determination of the number of RAD51 molecules in different human cell lines 

      Foertsch, Franziska; Kache, Tom; Drube, Sebastian; Biskup, Christoph; Nasheuer, Heinz-Peter; Melle, Christian (Taylor & Francis, 2019-11-15)
      Knowledge about precise numbers of specific molecules is necessary for understanding and verification of biological pathways. The RAD51 protein is central in the repair of DNA double-strand breaks (DSBs) by homologous ...

    • Spontaneous solid-state cocrystallization of caffeine and urea 

      MacFhionnghaile, Pól; Crowley, Clare M.; McArdle, Patrick; Erxleben, Andrea (American Chemical Society, 2020-01-09)
      The cocrystallization of caffeine and urea was monitored and analyzed using infrared spectroscopy, Raman microscopy, scanning electron microscopy, differential scanning calorimetry, and X-ray diffraction. The caffeine-urea ...