Browsing College of Science by Subject "ASSOCIATION"

Now showing items 1-3 of 3

    • Altered gene regulation as a candidate mechanism by which ciliopathy gene SDCCAG8 contributes to schizophrenia and cognitive function 

      Flynn, Mairéad; Whitton, Laura; Donohoe, Gary; Morrison, Ciaran G.; Morris, Derek W. (Oxford University Press (OUP), 2019-12-23)
      Mutations in genes that encode centrosomal/ciliary proteins cause severe cognitive deficits, while common single-nucleotide polymorphisms in these genes are associated with schizophrenia (SZ) and cognition in genome-wide ...

    • Arsenic in groundwater in south west Ireland: Occurrence, controls, and hydrochemistry 

      McGrory, Ellen; Holian, Emma; Alvarez-Iglesias, Alberto; Bargary, Norma; McGillicuddy, Eoin J.; Henry, Tiernan; Daly, Eve; Morrison, Liam (Frontiers Media, 2018-12-18)
      Globally numerous regions have been identified with elevated arsenic within groundwater which can result in potential adverse health risks. In Ireland, a previous national-scale research assessment of groundwater identified ...

    • Cognitive analysis of schizophrenia risk genes that function as epigenetic regulators of gene expression 

      Whitton, Laura; Cosgrove, Donna; Clarkson, Christopher; Harold, Denise; Kendall, Kimberley; Richards, Alex; Mantripragada, Kiran; Owen, Michael J.; O'Donovan, Michael C.; Walters, James; Hartmann, Annette; Konte, Betina; Rujescu, Dan; Gill, Michael; Corvin, Aiden; Rea, Stephen; Donohoe, Gary; Morris, Derek W. (Wiley, 2016-10-20)
      Epigenetic mechanisms are an important heritable and dynamic means of regulating various genomic functions, including gene expression, to orchestrate brain development, adult neurogenesis, and synaptic plasticity. These ...