Browsing College of Science by Title
Now showing items 206-225 of 976
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Determination of the number of RAD51 molecules in different human cell lines
(Taylor & Francis, 2019-11-15)Knowledge about precise numbers of specific molecules is necessary for understanding and verification of biological pathways. The RAD51 protein is central in the repair of DNA double-strand breaks (DSBs) by homologous ... -
Developing detailed chemical kinetic mechanisms for fuel combustion
(Elsevier, 2018-07-01)This paper discusses a brief history of chemical kinetic modeling, with some emphasis on the development of chemical kinetic mechanisms describing fuel oxidation. At high temperatures, the important reactions tend to be ... -
Development of a 5-component gasoline surrogate model using recent advancements in the detailed H2/O2/CO/C1-C3 mechanism for decoupling methodology
(Elsevier, 2020-08-17)In the present work, a 5-component gasoline surrogate chemical kinetic mechanism has been developed and validated. The first novelty of this mechanism is that a recently advanced H2/O2/CO/C1 detailed sub-mechanism is ... -
Development of a joint hydrogen and syngas combustion mechanism based on an optimization approach
(Wiley, 2016-05-20)A comprehensive and hierarchical optimization of a joint hydrogen and syngas combustion mechanism has been carried out. The Keromnes et al. (Combust Flame, 2013, 160, 995-1011) mechanism for syngas combustion was updated ... -
Development of a rapid Polarized Total Synchronous Fluorescence Spectroscopy (pTSFS) method for protein quantification in a model bioreactor broth
(Wiley, 2021-01-27)Protein quantification during bioprocess monitoring is essential for biopharmaceutical manufacturing and is complicated by the complex chemical composition of the bioreactor broth. Here we present the early-stage development ... -
Development of an ethogram for hutch-housed dairy calves and determination of factors influencing their behaviour
(Elsevier, 2020-11-18)The objectives of this study were to investigate the behaviour of hutch-housed dairy calves, develop an ethogram of general behaviour, and determine whether housing calves in different hutches, day, gender and time of day ... -
Development of Mcl-1 inhibitors for cancer therapy
(Elsevier, 2020-11-24)The myeloid leukemia cell differentiation protein (Mcl-1) is an anti-apoptotic protein of the B-cell lymphoma 2 (Bcl-2) family, which regulates cellular apoptosis. Mcl-1 expression plays a key role in survival of cancer ... -
Development of multipurpose skeletal core combustion chemical kinetic mechanisms
(American Chemical Society, 2021-03-25)Core combustion kinetic mechanisms for small C0¿C4 fuel molecules are not only of the utmost importance in understanding their individual combustion properties but are also the foundation for the development of kinetic ... -
Differences in tension and compression in the nonlinearly elastic bending of beams
(Texas Digital Library, 2009-02)The classical flexure problem of non-linear incompressible elasticity is revisited for elastic materials whose mechanical response is different in tension and compression - the so-called bimodular materials. The flexure ... -
Diffusionrank: a possible penicillin for web spamming
(2007)While the PageRank algorithm has proven to be very effective for ranking Web pages, the rank scores of Web pages can be manipulated. To handle the manipulation problem and to cast a new insight on the Web structure, we ... -
Discovery and recovery of an exceptional accumulation of carboniferous echinoids at Hook Head, Wexford
(Royal Irish Academy, 2022-09-30)Geoconservation is a burgeoning area of activity within the Earth sciences and the preservation of significant fossil finds remains crucial for the advancement of palaeontological knowledge and protection of geoheritage. ... -
Discovery of a faint X-ray counterpart and of a parsec-long X-ray tail for the middle-aged, gamma-ray only pulsar PSR J0357+3205
(2011)The Large Area Telescope (LAT) onboard the Fermi satellite opened a new era for pulsar astronomy, detecting gamma-ray pulsations from more than 60 pulsars, ~40% of which are not seen at radio wavelengths. One of the most ... -
Discovery of anti-cancer activity for benzo[1,2,4]triazin-7-ones: Very strong correlation to pleurotin and thioredoxin reductase inhibition
(Elsevier, 2016-05-30)The thioredoxin (Trx)-thioredoxin reductase (TrxR) system plays a key role in maintaining the cellular redox balance with Trx being over-expressed in a number of cancers. Inhibition of TrxR is an important strategy for ... -
The Discovery of gamma-Ray Emission From The Blazar RGB J0710+591
(2010)The high-frequency-peaked BL Lacertae object RGB J0710+591 was observed in the very high-energy (VHE; E > 100 GeV) wave band by the VERITAS array of atmospheric Cherenkov telescopes. The observations, taken between 2008 ... -
Discovery of Spectral Variability of Markarian 421 at TeV Energies
(2002)The detection of spectral variability of the gamma-ray blazar Mrk 421 at TeV energies is reported. Observations with the Whipple Observatory 10m gamma-ray telescope taken in 2000/2001 revealed exceptionally strong and ... -
Discovery of TeV Gamma Ray Emission from Tycho's Supernova Remnant
(2011)We report the discovery of TeV gamma-ray emission from the Type Ia supernova remnant (SNR) G120.1+1.4, known as Tycho's supernova remnant. Observations performed in the period 2008-2010 with the VERITAS ground-based gamma-ray ... -
Discovery of Variability in the Very High Energy Gamma-Ray Emission of 1ES 1218+304 with VERITAS
(2010)We present results from an intensive VERITAS monitoring campaign of the high-frequency peaked BL Lac object 1ES 1218+304 in 2008/2009. Although 1ES 1218+304 was detected previously by MAGIC and VERITAS at a persistent level ... -
Discovery of Very High-Energy Gamma-Ray Radiation from the BL Lac 1ES 0806+524
(2008)The high-frequency-peaked BL-Lacertae object \objectname{1ES 0806+524}, at redshift z=0.138, was observed in the very-high-energy (VHE) gamma-ray regime by VERITAS between November 2006 and April 2008. These data encompass ... -
Discovery of VHE $\gamma$-ray emission from the SNR G54.1+0.3
(2010)We report the discovery of very high energy gamma-ray emission from the direction of the SNR G54.1+0.3 using the VERITAS ground-based gamma-ray observatory. The TeV signal has an overall significance of 6.8$\sigma$ and ... -
A discrete P⋅⋅⋅I I⋅⋅⋅P assembly: the large influence of weak interactions on the 31P NMR Spectra of Phosphane–Diiodine Complexes
(Wiley, 2006-02-06)Seeing I to I: The reaction of a weakly coordinating carboranyl phosphane ligand with I2 leads to the formation of an adduct containing the bridging P⋅⋅⋅I[BOND]I⋅⋅⋅P assembly in the solid state (see picture; I purple, P ...