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A Highly Effective Gene Delivery Vector

ARAN - Access to Research at NUI Galway

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dc.contributor.author Newland, Ben en
dc.contributor.author Tai, Hongyun en
dc.contributor.author Zheng, Yu en
dc.contributor.author Velasco, Diego en
dc.contributor.author Di Luca, Andrea en
dc.contributor.author Howdle, Steven M. en
dc.contributor.author Alexander, Cameron en
dc.contributor.author Wang, Wenxin en
dc.contributor.author Pandit, Abhay en
dc.date.accessioned 2010-10-14T09:36:46Z en
dc.date.available 2010-10-14T09:36:46Z en
dc.date.issued 2010-06 en
dc.identifier.citation Newland, B., Tai, H., Zheng, Y., Velasco, D., Di Luca, A., Howdle, S. M., et al. A highly effective gene delivery vector - hyperbranched poly(2-(dimethylamino)ethyl methacrylate) from in situ deactivation enhanced ATRP. Chemical Communications, 46(26), 4698-4700. en
dc.identifier.issn 1359-7345 en
dc.identifier.uri http://hdl.handle.net/10379/1340 en
dc.description.abstract A hyperbranched 2-(dimethylamino)ethyl methacrylate (DMAEMA) based polymer has been synthesised by a one-pot in situ deactivation enhanced atom transfer radical polymerisation (DE-ATRP); it exhibits much higher transfection ability than linear poly(DMAEMA) and is comparable to the well known branched poly(ethylene imine) (PEI) and the SuperFect dendrimer but with lower cytotoxicity. en
dc.format application/pdf en
dc.publisher The Royal Society of Chemistry en
dc.subject Gene delivery en
dc.subject Network of Excellence for Functional Biomaterials en
dc.title A Highly Effective Gene Delivery Vector en
dc.type Article en
dc.local.publishedsource http://dx.doi.org/10.1039/C0CC00439A en
dc.description.peer-reviewed peer-reviewed en

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