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A Highly Effective Gene Delivery Vector

ARAN - Access to Research at NUI Galway

Show simple item record Newland, Ben en Tai, Hongyun en Zheng, Yu en Velasco, Diego en Di Luca, Andrea en Howdle, Steven M. en Alexander, Cameron en Wang, Wenxin en Pandit, Abhay en 2010-10-14T09:36:46Z en 2010-10-14T09:36:46Z en 2010-06 en
dc.identifier.citation Newland, B., Tai, H., Zheng, Y., Velasco, D., Di Luca, A., Howdle, S. M., et al. A highly effective gene delivery vector - hyperbranched poly(2-(dimethylamino)ethyl methacrylate) from in situ deactivation enhanced ATRP. Chemical Communications, 46(26), 4698-4700. en
dc.identifier.issn 1359-7345 en
dc.identifier.uri en
dc.description.abstract A hyperbranched 2-(dimethylamino)ethyl methacrylate (DMAEMA) based polymer has been synthesised by a one-pot in situ deactivation enhanced atom transfer radical polymerisation (DE-ATRP); it exhibits much higher transfection ability than linear poly(DMAEMA) and is comparable to the well known branched poly(ethylene imine) (PEI) and the SuperFect dendrimer but with lower cytotoxicity. en
dc.format application/pdf en
dc.publisher The Royal Society of Chemistry en
dc.subject Gene delivery en
dc.subject Network of Excellence for Functional Biomaterials en
dc.title A Highly Effective Gene Delivery Vector en
dc.type Article en
dc.local.publishedsource en
dc.description.peer-reviewed peer-reviewed en

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