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Spinal cord injury in vitro: Modelling axon growth inhibition

ARAN - Access to Research at NUI Galway

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dc.contributor.author Abu-Rub, Mohammad en
dc.contributor.author McMahon, Siobhan en
dc.contributor.author Zeugolis, Dimitrios I. en
dc.contributor.author Pandit, Abhay en
dc.date.accessioned 2010-10-14T09:15:39Z en
dc.date.available 2010-10-14T09:15:39Z en
dc.date.issued 2010-06 en
dc.identifier.citation Abu-Rub, M., McMahon, S., Zeugolis, D. I., Windebank, A., & Pandit, A. Spinal cord injury in vitro: modelling axon growth inhibition. Drug Discovery Today, 15(11-12), 436-443. en
dc.identifier.issn 1359-6446 en
dc.identifier.uri http://hdl.handle.net/10379/1336 en
dc.description.abstract Over the past three decades, tremendous progress has been made in elucidating mechanisms underlying regenerative failure after spinal cord injury and in devising therapeutic approaches to promote functional nerve regeneration. Various in vitro assays have been developed using brain and/or spinal cord neuronal cells to study axon growth in conditions that represent the post-injury environment. This review outlines the current models used to dissect, analyze and manipulate specific aspects of spinal cord injury leading to axon growth inhibition. en
dc.format application/pdf en
dc.publisher Elsevier en
dc.subject Spinal cord injury en
dc.subject Regenerative failure en
dc.subject Network of Excellence for Functional Biomaterials en
dc.title Spinal cord injury in vitro: Modelling axon growth inhibition en
dc.type Article en
dc.description.peer-reviewed peer-reviewed en

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