Browsing Surgery (Scholarly Articles) by Author "http://dx.doi.org/10.13039/100010414"
Now showing items 1-3 of 3
-
Mesenchymal Stem Cells (MSCs) and cancer: tumour specific delivery vehicles or therapeutic targets?
Dwyer, Róisín M.; Kerin, Michael J. (Mary Ann Liebert, 2010-09-30)Mesenchymal stem cells (MSCs) are a subset of nonhematopoietic multipotent cells found primarily within the bone marrow stroma. The ability of MSCs to specifically home to sites of tumors and their metastases, while escaping ... -
Potential role of mesenchymal stem cells (MSCs) in the breast tumour microenvironment: stimulation of epithelial to mesenchymal transition (EMT)
Martin, F. T.; Dwyer, Róisín M.; Kelly, J.; Khan, S.; Murphy, J. M.; Curran, C.; Miller, N.; Hennessy, E.; Dockery, P.; Barry, F. P.; O'Brien, T.; Kerin, Michael J. (Springer, 2010-01-20)Bone marrow-derived mesenchymal stem cells (MSCs) are known to specifically migrate to and engraft at tumour sites. Understanding interactions between cancer cells and MSCs has become fundamental to determining whether ... -
Systemic chemokine levels in breast cancer patients and their relationship with circulating menstrual hormones
Potter, Shirley M.; Dwyer, Róisín M.; Curran, Catherine E.; Hennessy, Emer; Harrington, Kate A.; Griffin, Damian G.; Kerin, Michael J. (Springer, 2008-06-04)Introduction The chemokines Stromal Cell-Derived Factor-1 alpha (SDF-1 alpha/CXCL12) and Monocyte Chemotactic Protein-1 (MCP-1/CCL2) have been implicated in breast cancer progression. We recently reported elevated systemic ...