Browsing School of Chemistry (Scholarly Articles) by Author "Ryder, Alan G."
Now showing items 21-40 of 58
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Frequency domain fluorescence lifetime study of crude petroleum oils
Owens, Peter; Ryder, Alan G.; Blamey, Nigel J. (Springer Verlag, 2008-02-01)Frequency domain (FD) fluorescence lifetime data was collected for a series of 20 crude petroleum oils using a 405 nm excitation source and over a spectral range of similar to 426 to similar to 650 nm. Average fluorescence ... -
Hydrocarbon fluid inclusion fluorescence: A review
Blamey, Nigel J.F.; Ryder, Alan G. (Springer, 2007)Geological fluid inclusions are small voids that can contain a variety of liquids which are often found in natural minerals and rocks. Typically they are less than 10 micrometres in size that host fossil fluids which existed ... -
Identifications and quantitative measurements of narcotics in solid mixtures using near-IR Raman spectroscopy and multivariate analysis
Ryder, Alan G.; O'Connor, G.M.; Glynn, T.J. (1999)Raman spectroscopy offers the potential for the identification of illegal narcotics in seconds by inelastic scattering of light from molecular vibrations. In this study cocaine, heroin, and MDMA were analyzed using near-IR ... -
Identifications and quantitative measurements of narcotics in solid mixtures using near-IR Raman spectroscopy and multivariate analysis.
Ryder, Alan G.; O Connor, Gerard M.; Glynn, Thomas J. (ASTM International, 1999)Raman spectroscopy offers the potential for the identification of illegal narcotics in seconds by inelastic scattering of light from molecular vibrations. In this study cocaine, heroin, and MDMA were analyzed using near-IR ... -
Influence of chemical composition on the fluorescence lifetimes of crude petroleum oils
Ryder, Alan G.; Glynn, Thomas J.; Feely, Martin (Society of Photo-optical Instrumentation Engineers, 2003)Fluorescence based methods are increasingly being used for the analysis of crude oils because they offer high speed, low cost, non-contact, and non-destructive testing options. The fluorescence of crude oils is due to the ... -
Investigating native state fluorescence emission of Immunoglobulin G using polarized Excitation Emission Matrix (pEEM) spectroscopy and PARAFAC
Steiner-Browne, Marina; Elcoroaristizabal, Saioa; Casamayou-Boucau, Yannick; Ryder, Alan G. (Elsevier, 2018-12-20)Intrinsic fluorescence spectroscopy (IFS) measurements for protein structural analysis can be enhanced by the use of anisotropy resolved multidimensional emission spectroscopy (ARMES). ARMES attempts to overcome the ... -
Investigating tryptophan quenching of fluorescein fluorescence under protolytic equilibrium
Ryder, Alan G.; Szczupak, Boguslaw; Togashi, Denisio M.; Calvet, Amandine; O'Loughlin, Muireann (2009)Fluorescein is one of most used fluorescent labels for characterizing biological systems, such as proteins, and is used in fluorescence microscopy. However, if fluorescein is to be used for quantitative measurements involving ... -
Kernel principal component analysis residual diagnosis (KPCARD): an automated method to remove cosmic ray artefacts in Raman spectra.
Li, Boyan; Calvet, Amandine; Casamayou-Boucau, Yannick; Ryder, Alan G. (2016)A new, fully automated, rapid method, referred to as kernel principal component analysis residual diagnosis (KPCARD), is proposed for removing cosmic ray artifacts (CRAs) in Raman spectra, and in particular for large Raman ... -
Low Temperature Fluorescence Studies of Crude Petroleum Oils
Owens, Peter; Ryder, Alan G. (2011)We have studied the low-temperature (133-298 K) fluorescence emission of crude petroleum oils using a combination of steady-state and time-resolved measurements. This was done, first, to see if we could generate linear ... -
Low-content quantification in powders using Raman spectroscopy: a facile chemometric approach to sub 0.1% limits of detection.
Li, Boyan; Calvet, Amandine; Ryder, Alan G.; Casamayou-Boucau, Yannick; Morris, Cheryl (American Chemical Society, 2015-02-23)A robust and accurate analytical methodology for low-content (<0.1%) quantification in the solid-state using Raman spectroscopy, sub-sampling, and chemometrics was demonstrated using a piracetam–proline model. The method ... -
Measuring the micro-polarity and hydrogen-bond donor/acceptor ability of thermoresponsive N-isopropylacrylamide/N-tert-butylacrylamide copolymer films using solvatochromic indicators
Szczupak, Boguslaw; Ryder, Alan G.; Togashi, Denisio M.; Rochev, Yuri A.; Glynn, Thomas J. (application/pdf, 2009)Thin polymer films are important in many areas of biomaterials research, biomedical devices, and biological sensors. The accurate in situ measurement of multiple physicochemical properties of thin polymer films is critical ... -
Measuring the Micro-Polarity and Hydrogen-Bond Donor/Acceptor Ability of Thermoresponsive N-Isopropylacrylamide/N-tert-Butylacrylamide Copolymer Films Using Solvatochromic Indicators
Ryder, Alan G.; Szczupak, Boguslaw; Togashi, Denisio M.; Rochev, Yuri A.; Glynn, Thomas J. (2009)Thin polymer films are important in many areas of biomaterials research, biomedical devices, and biological sensors. The accurate in situ measurement of multiple physicochemical properties of thin polymer films is critical ... -
Modelling Förster resonance energy transfer (FRET) using anisotropy resolved multi-dimensional emission spectroscopy (ARMES)
Gordon, Fiona; Elcoroaristizabal, Saioa; Ryder, Alan G. (Elsevier, 2020-11-16)Background Förster Resonance Energy Transfer (FRET) is widely used to study the structure and dynamics of biomolecular systems and also causes the non-linear fluorescence response observed in multi-fluorophore proteins. ... -
Monitoring cell culture media degradation using surface enhanced Raman scattering (SERS) spectroscopy
Calvet, Amandine; Ryder, Alan G. (Elsevier (Science Direct), 2014-06-13)The quality of the cell culture media used in biopharmaceutical manufacturing is a crucial factor affecting bioprocess performance and the quality of the final product. Due to their complex composition these media are ... -
Monitoring local unfolding of bovine serum albumin during denaturation using steady-state and time-resolved fluorescence spectroscopy
Togashi, Denisio M.; Ryder, Alan G.; O'Shaughnessy, Domhnall (Springer, 2010-03)In a previous report (J. Fluoresc. 16, 153, 2006) we studied the chaotropiclly induced denaturation of Bovine Serum Albumin (BSA) using the fluorescence decay kinetics at different stages in the denaturation of BSA by ... -
Multi-attribute quality screening of immunoglobulin G using polarized Excitation Emission Matrix spectroscopy
de Faria E Silva, Ana Luiza; Elcoroaristizabal, Saioa; Ryder, Alan G. (Elsevier, 2019-12-10)Immunoglobulin G (IgG) is often used as a starting material for the production of functionalised antibodies, like Antibody Drug Conjugates (ADCs), PEGlyated-conjugates, or radioimmunoconjugates. The gross structural quality ... -
Performance Monitoring of a Mammalian Cell Based Bioprocess using Raman spectroscopy.
Ryder, Alan G.; Li, Boyan; Ray, Bryan H. (2013)Being able to predict the final product yield at all stages in long-running, industrial, mammalian cell culture processes is vital for both operational efficiency, process consistency, and the implementation of Quality by ... -
Prediction of Cell Culture Media Performance Using Fluorescence Spectroscopy
Ryan, Paul W.; Boyan, Li; Shanahan, Michael; Ryder, Alan G. (2010)Cell culture media used in industrial mammalian cell culture are complex aqueous solutions that are inherently difficult to analyze comprehensively. The analysis of media quality and variance is of utmost importance in ... -
Prediction of Cell Culture Media performance using Fluorescence Spectroscopy
Ryan, Paul W.; Li, Boyan; Shanahan, Michael; Ryder, Alan G. (ACS Publications, 2010)Cell culture media used in industrial mammalian cell culture are complex aqueous solutions that are inherently difficult to analyze comprehensively. The analysis of media quality and variance is of utmost importance in ... -
Prediction of cell culture media performance using fluorescence spectroscopy.
Ryan, Paul W.; Li, Boyan; Shanahan, Michael; Ryder, Alan G. (American Chemical Society, 2010)Cell culture media used in industrial mammalian cell culture are complex aqueous solutions that are inherently difficult to analyze comprehensively. The analysis of media quality and variance is of utmost importance in ...