Browsing School of Chemistry by Author "Science Foundation Ireland"

Now showing items 1-5 of 5

    • Dual-drug amorphous formulation of gliclazide 

      Aljohani, Marwah; McArdle, Patrick; Erxleben, Andrea (Taylor and Francis, 2021-02-01)
      Amorphization is a well-established strategy to enhance the dissolution properties of poorly water-soluble drugs. However, the amorphous state is inherently unstable toward recrystallization. Coamorphous systems of a drug ...

    • An experimental, theoretical, and modeling study of the ignition behavior of cyclopentanone 

      Zhang, Kuiwen; Lokachari, Nitin; Ninnemann, Erik; Khanniche, Sarah; Green, William H.; Curran, Henry J.; Vasu, Subith S.; Pitz, William J. (Elsevier, 2018-07-05)
      The ignition delay times of cyclopentanone in air were measured using a high pressure shock tube (HPST) and a rapid compression machine (RCM) over the temperature range of 794-1368 K at P = 15 and 30 bar and at equivalence ...

    • A hierarchical single-pulse shock tube pyrolysis study of C-2-C-6 1-alkenes 

      Nagaraja, Shashank S.; Liang, Jinhu; Dong, Shijun; Panigrahy, Snehasish; Sahu, Amrit; Kukkadapu, Goutham; Wagnon, Scott W.; Pitz, William J.; Curran, Henry J. (Elsevier, 2020-06-27)
      A single-pulse shock tube study of the pyrolysis of 2% C-2 - C-6 1-alkenes is presented at 2 bar in the tem-perature range 900-1800 K in the current study. Reactant, intermediate and product species are obtained and ...

    • Low Temperature Fluorescence Studies of Crude Petroleum Oils 

      Owens, Peter; Ryder, Alan G. (2011)
      We have studied the low-temperature (133-298 K) fluorescence emission of crude petroleum oils using a combination of steady-state and time-resolved measurements. This was done, first, to see if we could generate linear ...

    • Synthesis of migrastatin analogues as inhibitors of tumour cell migration: Exploring structural change in and on the macrocyclic ring 

      Lo Re, Daniele; Zhou, Ying; Mucha, Joanna; Jones, Leigh F.; Leahy, Lorraine; Santocanale, Corrado; Krol, Magdalena; Murphy, Paul V. (Wiley, 2015-11-04)
      Migrastatin and isomigrastatin analogues have been synthesised in order to contribute to structure-activity studies on tumour cell migration inhibitors. These include macrocycles varying in ring size, functionality and ...