Browsing by Author "van Vuuren, Chelly"
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Premitotic Assembly of Human CENPs -T and -W Switches Centromeric Chromatin to a Mitotic State.
Prendergast, Lisa; van Vuuren, Chelly; Kaczmarczyk, Agnieszka; Quinn, Nadine; Sullivan, Kevin F. (2011)Centromeres are differentiated chromatin domains, present once per chromosome, that direct segregation of the genome in mitosis and meiosis by specifying assembly of the kinetochore. They are distinct genetic loci in that ... -
A refined model of nucleolar formation derived from the analysis of UBF variants and the hierarchical silencing of human nucleolar organizer regions
van Vuuren, Chelly (NUI Galway, 2017-03-23)The nucleolus, the largest sub-nuclear structure, forms around arrays of ribosomal RNA genes, termed nucleolar organizer regions (NORs). As the site of ribosome biogenesis, nucleolar function is intrinsically linked to ...