Browsing by Subject "formalin test"
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A role for pparα in the medial prefrontal cortex in formalin-evoked nociceptive responding in rats
(Wiley-Blackwell, 2014-03-01)Background and PurposeThe nuclear hormone receptor, PPAR, and its endogenous ligands, are involved in pain modulation. PPAR is expressed in the medial prefrontal cortex (mPFC), a key brain region involved in both the ... -
Enhanced nociceptive responding in two rat models of depression is associated with alterations in monoamine levels in discrete brain regions
(2010)Altered pain responding in depression is a widely recognized but poorly understood phenomenon The present study investigated nociceptive responding to acute (thermal and mechanical) and persistent (inflammatory) noxious ...