Browsing by Author "Zheng, Yu"
Now showing items 1-6 of 6
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Controlled multi-vinyl monomer homopolymerization through vinyl oligomer combination as a universal approach to hyperbranched architectures
Zhao, Tianyu; Zheng, Yu; Poly, Julien; Wang, Wenxin (Springer Nature, 2013-05-21)The three-dimensional structures of hyperbranched materials have made them attractive in many important applications. However, the preparation of hyperbranched materials remains challenging. The hyperbranched materials ... -
DNA Immobilization and Detection on Cellulose Paper using a Surface Grown Cationic Polymer via ATRP
Aied, Ahmed; Zheng, Yu; Pandit, Abhay (American Chemical Society, 2012-02-02)Cationic polymers with various structures have been widely investigated in the areas of medical diagnostics and molecular, biology because of their unique binding properties and capability to interact with biological ... -
A Fluorescently Labeled, Hyperbranched Polymer Synthesized from DE-ATRP for the Detection of DNA Hybridization
Aied, Ahmed; Glynn, Barry; Cao, Hongliang; Zheng, Yu; Pandit, Abhay; Wang, Wenxin (Royal Society of Chemistry, 2012-01)The early detection of oligonucleotide biomarkers of disease, such as microRNAs, has been established as a fundamental factor in cancer diagnosis. As the levels of these small molecules (microRNAs) in blood have recently ... -
A Highly Effective Gene Delivery Vector
Newland, Ben; Tai, Hongyun; Zheng, Yu; Velasco, Diego; Di Luca, Andrea; Howdle, Steven M.; Alexander, Cameron; Wang, Wenxin; Pandit, Abhay (The Royal Society of Chemistry, 2010-06)A hyperbranched 2-(dimethylamino)ethyl methacrylate (DMAEMA) based polymer has been synthesised by a one-pot in situ deactivation enhanced atom transfer radical polymerisation (DE-ATRP); it exhibits much higher transfection ... -
Single Cyclized Molecule Structure from RAFT Homopolymerization of Multi-vinyl Monomers
Zheng, Yu; Newland, Ben; Pandit, Abhay; Wang, Wenxin (2012)We explore a kinetically controlled strategy to suppress the gelation in the homopolymerization of multi-vinyl monomers (MVMs) via RAFT polymerization. We report the generation of 3D single cyclized polymer structures from ... -
Single Cyclized Molecule Versus Single Branched Molecule: A Simple and Efficient 3D "Knot" Polymer Structure for Nonviral Gene Delivery
Newland, Ben; Zheng, Yu; Jin, Yao; Abu-Rub, Mohammad; Cao, Hongliang; Wang, Wenxin; Pandit, Abhay (American Chemical Society, 2012-02-12)The large research effort focused on enhancing nonviral transfection vectors has clearly demonstrated that their macromolecular structure has a significant effect on their transfection efficacy. The 3D branched polymeric ...