Now showing items 1-5 of 5

    • A germline mutation in the brca13’utr predicts stage iv breast cancer 

      Dorairaj, Jemima J; Salzman, David W; Wall, Deirdre; Rounds, Tiffany; Preskill, Carina; Sullivan, Catherine AW; Lindner, Robert; Curran, Catherine; Lezon-Geyda, Kim; McVeigh, Terri; Harris, Lyndsay; Newell, John; Kerin, Michael J; Wood, Marie; Miller, Nicola; Weidhaas, Joanne B (Springer Nature, 2014-06-10)
      Background: A germline, variant in the BRCA1 3'UTR (rs8176318) was previously shown to predict breast and ovarian cancer risk in women from high-risk families, as well as increased risk of triple negative breast cancer. ...
    • Investigating the impact of genomic profiling on breast cancer risk prediction, treatment and outcome 

      McVeigh, Terri (2018-02-05)
      It has, for many years, been acknowledged that “breast cancer” is an umbrella term for many genetically and immunophenotypically distinct malignancies of the breast. Treatment paradigms are shifting in direct response to ...
    • The KRAS-Variant Is Associated with Risk of Developing Double Primary Breast and Ovarian Cancer 

      Kerin, Michael J.; McVeigh, Terri; Dorairaj, Jemima J.; Heneghan, Helen M.; Miller, Nicola (2012)
      Purpose: A germline microRNA binding site-disrupting variant, the KRAS-variant (rs61764370), is associated with an increased risk of developing several cancers. Because this variant is most strongly associated with ovarian ...
    • The acquisition and retention of urinary catheterisation skills using surgical simulator devices: teaching method or student traits 

      Waters, Peadar S; McVeigh, Terri; Kelly, Brian D; Flaherty, Gerard T; Devitt, Dara; Barry, Kevin; Kerin, Michael J (Springer Nature, 2014-12-01)
      Background: The acquisition of procedural skills is an essential component of learning for medical trainees. The objective of this study was to assess which teaching method of performing urinary catheterisation is associated ...
    • The kras-variant is associated with risk of developing double primary breast and ovarian cancer 

      Pilarski, Robert; Patel, Divya A.; Weitzel, Jeffrey; McVeigh, Terri; Dorairaj, Jemima J.; Heneghan, Helen M.; Miller, Nicola; Weidhaas, Joanne B.; Kerin, Michael J.; McKenna, Megan; Wu, Xifeng; Hildebrandt, Michelle; Zelterman, Daniel; Sand, Sharon; Shulman, Lee P. (Public Library of Science (PLoS), 2012-05-25)
      Purpose: A germline microRNA binding site-disrupting variant, the KRAS-variant (rs61764370), is associated with an increased risk of developing several cancers. Because this variant is most strongly associated with ovarian ...