Browsing by Author "McCormack, Grace P"
Now showing items 1-4 of 4
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Characterizing the emergence and persistence of drug resistant mutations in hiv-1 subtype c infections using 454 ultra deep pyrosequencing
Bansode, Vijay; McCormack, Grace P; Crampin, Amelia C; Ngwira, Bagrey; Shrestha, Ram K; French, Neil; Glynn, Judith R; Travers, Simon A (Springer Nature, 2013-01-30)Background: The role of HIV-1 RNA in the emergence of resistance to antiretroviral therapies (ARTs) is well documented while less is known about the role of historical viruses stored in the proviral DNA. The primary focus ... -
Drug resistance, evolution and diversity of HIV-1 in Malawi
Bansode, Vijay Balasaheb (2012-09-07) -
Qtrim: a novel tool for the quality trimming of sequence reads generated using the roche/454 sequencing platform
Shrestha, Ram; Lubinsky, Baruch; Bansode, Vijay B; Moinz, Mónica BJ; McCormack, Grace P; Travers, Simon A (Springer Nature, 2014-01-01)Background: Many high throughput sequencing (HTS) approaches, such as the Roche/454 platform, produce sequences in which the quality of the sequence (as measured by a Phred-like quality scores) decreases linearly across a ... -
Reverse transcriptase drug resistance mutations in hiv-1 subtype c infected patients on art in karonga district, malawi
Bansode, Vijay B; Travers, Simon AA; Crampin, Amelia C; Ngwira, Bagrey; French, Neil; Glynn, Judith R; McCormack, Grace P (Springer Nature, 2011-01-01)Background: Drug resistance testing before initiation of, or during, antiretroviral therapy (ART) is not routinely performed in resource-limited settings. High levels of viral resistance circulating within the population ...