Browsing by Author "Kulkarni, Mangesh"
Now showing items 1-5 of 5
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Autologous circulating angiogenic cells treated with osteopontin and delivered via a collagen scaffold enhance wound healing in the alloxan-induced diabetic rabbit ear ulcer model
O’Loughlin, Aonghus; Kulkarni, Mangesh; Vaughan, Erin E; Creane, Michael; Liew, Aaron; Dockery, Peter; Pandit, Abhay; O’Brien, Timothy (Springer Nature, 2013-01-01)Introduction: Diabetic foot ulceration is the leading cause of amputation in people with diabetes mellitus. Peripheral vascular disease is present in the majority of patients with diabetic foot ulcers. Despite standard ... -
Fibrin as a scaffold for delivery of GDNF overexpressing stem cells to the adult rat brain
Moloney, Teresa C.; Kulkarni, Mangesh; Ní Fhlathartaigh1, Mary; Abhay, Pandit; Dowd, Eilís (2017-04-05)Treatment of neurodegenerative disease is entering a new era where direct intracerebral delivery of therapeutic factors aims to restore normality to dysfunctional circuits. Cell-based therapeutic approaches, where virally ... -
Fibrin Mediated Proangiogenic and Secretory Control Gene Therapy for Compromised Wound Healing
Kulkarni, Mangesh (2012-07-18)Chronic or compromised healing is a major clinical problem. Particularly, in diabetes where the disease process hinders the capacity to repair the tissue damage, the patients are more susceptible to chronic ulcers, especially ... -
Liposomal gene delivery mediated by tissue-engineered scaffolds
Kulkarni, Mangesh; Greiser, Udo; O’Brien, Timothy; Pandit, Abhay (Elsevier BV, 2010-01-01)In the absence of any ideal gene delivery carrier despite the recent explosion of novel carrier systems, the current trend is to explore the complementary synergy promised by a combination of delivery systems such as ... -
Liposomal gene delivery mediated by tissue-engineered scaffolds
Kulkarni, Mangesh; Griser, Udo; O'Brien, Timothy; Pandit, Abhay (Elsevier, 2010-01-01)In the absence of any ideal gene delivery carrier despite the recent explosion of novel carrier systems, the current trend is to explore the complementary synergy promised by a combination of delivery systems such as ...