Browsing by Author "Irish Cancer Society"
Now showing items 1-7 of 7
-
Circulating MicroRNAs in cancer
O’Brien, Killian P.; Ramphul, Eimear; Howard, Linda; Gallagher, William M.; Malone, Carmel; Kerin, Michael J.; Dwyer, Róisín M. (Humana Press, 2016-11-09)It is believed that microRNAs have potential as circulating biomarkers of disease, however successful clinical implementation remains a challenge. This chapter highlights broad variations in approaches to microRNA analysis ... -
Environmental Health Organisations against Tobacco
Byrne, Miriam (2009) -
Identifying novel strategies to re-engage the apoptotic pathway for the treatment of cancer
Halpin-McCormick, Anna (2014-09-30)In chapter two we demonstrate that in non-transformed cells multiple signalling pathways control TRAIL resistance and they act in a redundant manner. This is contrary, however, to the resistance mechanisms found in tumour ... -
Investigation of IRE1/XBP1s pathway and its potential as a therapeutic target in breast cancer
Cleary, Patricia (2015-09-18)X-Box binding protein 1 (XBP1) is an integral component of the unfolded protein response (UPR), a pro-survival mechanism, triggered by the onset of endoplasmic reticulum stress. Activation of the endoplasmic reticulum ... -
Legislation for smoke-free workplaces and health of bar workers in Ireland: before and after study
Pursell, Lisa; DeAth, Maureen; O'Donovan, Diarmuid (BMJ Group, 2005-10)Objectives - To compare exposure to secondhand smoke and respiratory health in bar staff in the Republic of Ireland and Northern Ireland before and after the introduction of legislation for smoke-free workplaces in the ... -
MicroRNAs as biomarkers and therapeutics in breast cancer
O'Brien, Killian (2017-05-25)Micro(mi)RNAs have potential as both therapeutics and circulating biomarkers of disease. This study investigates potential breast cancer biomarkers miR-138, miR-504 and miR-379. Furthermore, it investigates the impact that ... -
Secondhand smoke exposure and risk following the Irish smoking ban: an assessment of salivary cotinine concentrations in hotel workers and air nicotine levels in bars
Mulcahy, M; Evans, D; Hammond, S; Repace, J; Byrne, M (BMJ Group, 2005-12)Objective: To investigate whether the Irish smoking ban has had an impact on secondhand smoke (SHS) exposures for hospitality workers. Design, setting, and participants: Before and after the smoking ban a cohort of ...