Browsing by Subject "Glycomimetics"
Now showing items 1-3 of 3
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Design, synthesis and evaluation of glycomimetics as galectin inhibitors
(NUI Galway, 2024-03-11)Chapter-1: This chapter begins with a short review on carbohydrates and their structure and then summarises some highlights from the last two decades of research on developing carbohydrate-based drug candidates. Included ... -
Synthesis of an orthogonally protected polyhydroxylated cyclopentene from L-Sorbose
(Chemical Editorial Society (ACES) / Wiley, 2016-07-06)The use of l-sorbose in the synthesis of functionalized cyclopentene derivatives was accomplished. These cyclopentene derivatives are related to those found in naturally occurring jatrophane frameworks and in other bioactive ... -
Synthesis of bivalent glycoclusters containing GlcNAc as hexasaccharide mimetics. Bactericidal activity against Helicobacter pylori.
(Elsevier, 2012-07-27)The Cu(I) catalysed cycloaddition reaction of azides and alkynes has been used to generate a series of divalent GlcNAc clusters with both α and β configurations. These glycoclusters can be considered as potential mimetics ...