Browsing by Subject "Finite element modelling"
Now showing items 1-15 of 15
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Computational investigation of in situ chondrocyte deformation and actin cytoskeleton remodelling under physiological loading
(Elsevier, 2012-12-24)Previous experimental studies have determined local strain fields for both healthy and degenerate cartilage tissue during mechanical loading. However, the biomechanical response of chondrocytes in situ, in particular the ... -
A computational investigation of the laser bonding of balloon catheters
(2015-09-28)The balloon catheters produced by Boston Scientific are manufactured using a laser bonding process. The behaviour of the materials during this laser welding process is not very well understood. In this work a computational ... -
Computational modelling of the coupled electro-mechanical behaviour of neurons
(NUI Galway, 2019-01-22)Recent experimental evidence has uncovered complex biophysical phenomena accompanying the electrical activity of nervous cells. Now emerging theories refer to the electric pulse, i.e. the Action Potential (AP), as an ... -
The Development of a Computational Test-Bed to Assess Coronary Stent Implantation
(2013-03-15)The implantation behaviour of coronary stents is of great interest to clinicians and engineers alike as in-stent restenosis (ISR) remains a critical issue with the community. ISR is hypothesized to occur for ... -
Development of advanced numerical models for concentrically braced steel frame members and components
(NUI Galway, 2018-09-18)The behaviours of braced steel frame members and components are investigated in this project using finite element models that were developed to address the multi-scale mechanics of braced steel frame structures. The ... -
An experimental and computational investigation into procedural complications relating to transcatheter aortic heart valves
(NUI Galway, 2018-02-20)Although transcatheter aortic valves are widely used for treatment of high to medium risk patients with severe aortic stenosis, there are still many associated procedural complications. In particular, new on-set conductance ... -
Experimental and computational investigation of the active force generation of cells subjected to static and dynamic loading
(2016-05-13)The development of a mechanistic understanding of the processes by which cells sense and actively respond to the mechanical environment would represent a significant advance in the fields of biomechanics and tissue ... -
Experimental and numerical characterisation of materials for biomass co-firing
(2017-02-23)As Europe continues to decarbonize its electricity generation capacity, operators of thermal power plants face challenges to which they must adapt including increasingly transient operation and co-firing with biomass. This ... -
Experimental investigation, numerical modelling and multi-objective optimisation of composite wind turbine blades
(Taylor & Francis, 2017-05-24)Static load and modal testing of two blades from a 15 kW wind turbine is presented. The two blades are made from glass fibre-reinforced polypropylene, one of which has been reinforced with additional carbon fibre plies. ... -
Finite element modelling for component-level additive manufacturing applied to residual stress-deformation mitigation and fatigue crack initiation in welded connections
(NUI Galway, 2023-08-21)Additive manufacturing (AM) has attracted significant attention in many applications due to its capability of fabricating complex and customized metal parts. However, the potential for high inherent residual stresses ... -
Head-to-nerve analysis of electromechanical impairments of diffuse axonal injury
(Springer, 2018-11-14)The aim was to investigate mechanical and functional failure of diffuse axonal injury (DAI) in nerve bundles following frontal head impacts, by finite element simulations. Anatomical changes following traumatic brain injury ... -
Micromechanics of fatigue with application to stents
(2014-09-30)This thesis describes the development of a computational framework, based on experimental characterisation and validation, for the microstructure-sensitive modelling of fatigue crack initiation, with a focus placed on its ... -
Modelling the degradation and elastic properties of poly(lactic-co-glycolic acid) films and regular open -cell tissue engineering scaffolds
(Elsevier, 2015-09-02)Scaffolding plays a critical rule in tissue engineering and an appropriate degradation rate and sufficient mechanical integrity are required during degradation and healing of tissue. This paper presents a computational ... -
Modelling the mechanical and fatigue behaviour of superelastic NiTi: analysing the role of microstructural phase and crystallographic texture
(2015-08-26)Superelastic NiTi self-expanding stents push the boundaries of our current understanding of material behaviour which ultimately influences the design of biomedical devices. In particular, the influence of microstructure ... -
The Response of Cells to the Mechanical Environment: A Numerical Investigation of the Actin Cytoskeleton and Cell Adhesion
(2012-10-21)Numerous in-vitro studies have established that cells possess the ability to sense and react to their physical environment. However, the mechanisms underlying such mechanotransduction are poorly understood. Previous cell ...