Browsing by Subject "Drug resistance"
Now showing items 1-3 of 3
-
Mechanisms of bone marrow-mediated drug resistance in acute myeloid leukaemia
(NUI Galway, 2020-06-12)Acute myeloid leukaemia (AML) is a heterogenous clonal disorder characterised by the accumulation of immature, non-functional and highly proliferative blasts in the bone marrow and periphery. AML has a high relapse rate, ... -
Preclinical assessment of the novel compound EL102 in prostate cancer
(2015-03-31)Prostate cancer remains a growing problem for the male population, globally. Though there have been clinical advances in recent years, there still remains a need to develop drugs that can slow or stop progression beyond ... -
Revealing the Origin and Nature of Drug Resistance of Dynamic Tumour Systems
(2010)In this paper, the authors identify the strategies that resistant subpopulations of cancer cells undertake to overcome the effect of the anticancer drug Topotecan. For the analyses of cell lineage data encoded from timelapse ...