Browsing by Subject "Diabetes"
Now showing items 1-20 of 22
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Autologous peripheral blood endothelial progenitor cells as a potential therapy for diabetic critical limb ischemia
(NUI Galway, 2023-10-20)[No abstract] -
Building the evidence base for the development and implementation of an Irish national digital Type 2 Diabetes prevention programme
(NUI Galway, 2022-12-09)Background: Type 2 Diabetes Mellitus (T2DM) represents a major public health concern. Over one million annual deaths worldwide are attributed to the disease, making it the ninth leading cause of mortality. In Ireland, the ... -
A core outcome set for the treatment of pregnant women with pregestational diabetes: An international consensus study
(NUI Galway, 2021-09-10)Background Meaningful comparisons between studies evaluating interventions of pregnant women with pre-gestational diabetes mellitus (PGDM) are limited due to the heterogeneity in outcome selection and reporting. The aim ... -
Development of a mesenchymal stromal cell / collagen scaffold product for treatment of diabetic wounds
(NUI Galway, 2022-08-23)Foot ulceration is a major complication of diabetes mellitus, which results in significant human suffering and a major burden on healthcare systems. Mesenchymal stromal cells (MSCs) emerged as a promising therapeutic ... -
Development of novel biomaterials and medical devices to improve diabetes treatment and ambient cell transportation
(NUI Galway, 2023-02-08)Diabetes mellitus is a global pandemic affecting to more than 500 million people worldwide, with Type 1 diabetics being the most at risk due to life-threatening hyper and hypoglycaemic complications. Islet transplantation ... -
Diabetes mellitus and gender have a negative impact on the outcome of hip fracture surgery – a pilot study
(Wiley, 2019-11-07)Diabetes mellitus (DM) is associated with an elevated risk of post-operative complications. The impact it has on patients living with DM following hip fracture surgery (HFS) is not completely understood, and may represent ... -
Effects of an eight-week supervised, structured lifestyle modification programme on anthropometric, metabolic and cardiovascular risk factors in severely obese adults
(BioMed Central, 2015-08-01)Background Lifestyle modification is fundamental to obesity treatment, but few studies have described the effects of structured lifestyle programmes specifically in bariatric patients. We sought to describe changes in ... -
An experimental investigation on the biomechanics of bone fragility in type 2diabetes
(NUI Galway, 2023-10-11)Type 2 diabetic patients experience up to a 3-fold increase in bone fracture risk. Paradoxically, type 2 diabetes is associated with a normal or increased bone mineral density (BMD) when compared to non-diabetic patients. ... -
Exploring the effectiveness and implementation of goal-setting techniques in diabetes self-management interventions and structured education programme
(NUI Galway, 2018-09-28)Background. The treatment of diabetes consists of ongoing medical care and continuous self-management. Sub-optimal levels of diabetic control are commonly detected in people with diabetes. Therefore, Healthcare Professionals ... -
Fibrin Mediated Proangiogenic and Secretory Control Gene Therapy for Compromised Wound Healing
(2012-07-18)Chronic or compromised healing is a major clinical problem. Particularly, in diabetes where the disease process hinders the capacity to repair the tissue damage, the patients are more susceptible to chronic ulcers, especially ... -
Impaired cued and spatial learning performance and altered cannabinoid CB1 receptor functionality in the substantia nigra in a rat model of diabetic neuropathy
(Elsevier, 2016-01-13)Diabetes, and associated diabetic neuropathic pain, impact negatively on cognitive function. However, the underlying mechanisms remain poorly understood. This study investigated neuropathic pain-related behaviour and ... -
The importance of a continuum of care before, during and after pregnancy in women with type 1 and type 2 diabetes along the Irish Atlantic seaboard
(2017-04-06)Pregestational diabetes is the most common chronic medical condition to complicate pregnancy and is associated with an increased risk of morbidity and mortality for the mother-offspring pair. Optimising outcomes for this ... -
Investigating the management of diabetes in nursing homes using a mixed methods approach
(Elsevier ScienceDirect, 2017-03-21)Aims: As populations age there is an increased demand for nursing home (NH) care and a parallel increase in the prevalence of diabetes. Despite this, there is growing evidence that the management of diabetes in NHs is ... -
An investigation into weight mediated conditions as risk factors for the development of autism spectrum disorder in offspring and the application of applied behavior analysis to pre-pregnancy weight behavior
(NUI Galway, 2018-09-03)Obesity (OB) has been identified as one of the greatest health concerns of the present time, due to the universally increasing rates (WHO, 2016). It has been found that a large proportion of the rise of OB is among women ... -
Is diabetes self-management education still the Cinderella of diabetes care?
(Elsevier ScienceDirect, 2017-05-17)This paper reflects on the status of diabetes self-management education (DSME) as a branch of diabetology in Europe and discusses some opportunities for better supporting DSME delivery. DSME (also commonly known as Therapeutic ... -
A new measure of multimorbid illness and treatment representations: the example of diabetes and depression
(Elsevier ScienceDirect, 2015-03-15)Background: Depression is two to three times more common in people with diabetes than in the general population. Although multimorbid diabetes and depression is associated with poor health outcome, existing research has ... -
Novel Cell-Based Therapies for the Treatment of Diabetic Ulceration
(2012-02-28)The focus of this research is on developing novel cell based therapies for the treatment of non-healing diabetic foot ulceration. The thesis begins with a concise review of the diabetic foot ulcers. The burden associated ... -
The prevalence of abnormal glucose tolerance up to 5 years after an index pregnancy complicated by gestational diabetes defined using International Association of Diabetes and Pregnancy Study Groups criteria
(2015-09-25)Introduction Gestational diabetes (GDM) is associated with an increased future risk of type 2 diabetes, but the risk among women diagnosed with the International Association of Diabetes and Pregnancy Study Groups (IADPSG) ... -
Prioritising target behaviours for research in diabetes: Using the nominal group technique to achieve consensus from key stakeholders
(BioMed Central, 2016-04-06)The behaviour of people with diabetes (e.g. taking medication) and the behaviour of doctors and other healthcare professionals (e.g. checking patients' blood sugar) are important. Our research group wanted to select one ... -
The role of novel biomarkers in addressing the burden of chronic kidney disease in diabetes mellitus
(NUI Galway, 2022-10-06)Kidney disease due to diabetes (Diabetic Kidney Disease (DKD)) is the leading cause of chronic kidney disease worldwide. It is an underappreciated, often under-recognised component of the overall burden of diabetes. People ...