Browsing by Subject "DNA polymerase eta"

Now showing items 1-2 of 2

    • Characterisation of UVA-induced DNA damage responses in human skin cells 

      Conmy, Sarah Angela (2013-09-30)
      Accumulating evidence indicates that exposure to long-wavelength ultraviolet A (UVA) radiation (315-400 nm), which accounts for >95% of solar UV radiation reaching the earth's surface, is a significant risk factor for the ...

    • The rad30 cancer susceptibility gene 

      Carty, M.P.; Glynn, M.; Maher, M.; Smith, T.; Yao, J.; Dixon, K.; McCann, J.; Rynn, L.; Flanagan, A. (Portland Press Ltd., 2003-02-01)
      The human skin cancer-prone disease xeroderma pigmentosum variant (XPV) results from a mutation in RAD30, which encodes the novel lesion bypass DNA polymerase eta. XPV cells are characterized by delayed completion of DNA ...