Browsing by Author "Colleran, Christine"
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Structure-function analysis of hmo1 unveils an ancestral organization of hmg-box factors involved in ribosomal dna transcription from yeast to human
Albert, Benjamin; Colleran, Christine; Léger-Silvestre, Isabelle; Berger, Axel B.; Dez, Christophe; Normand, Christophe; Perez-Fernandez, Jorge; McStay, Brian; Gadal, Olivier (Oxford University Press (OUP), 2013-09-09)Ribosome biogenesis is a major metabolic effort for growing cells. In Saccharomyces cerevisiae, Hmo1, an abundant high-mobility group box protein (HMGB) binds to the coding region of the RNA polymerase I transcribed ribosomal ... -
Upstream Binding Factor, an Evolutionarily Conserved Protein that Organises Ribosomal Gene Chromatin
Colleran, Christine (2012-09-28)The nucleolus, the site of ribosome biogenesis, forms around arrays of ribosomal gene (rDNA) repeats termed nucleolar organiser regions (NORs). Transcriptionally active NORs appear as regions of under-condensed chromatin ...