Browsing by Subject "Antidepressants"
Now showing items 1-4 of 4
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Chronic administration of amitriptyline differentially alters neuropathic pain-related behaviour in the presence and absence of a depressive-like phenotype
(Elsevier, 2015-02)Chronic pain and depression share a complex, reciprocal relationship. Furthermore, in addition to treating depression, antidepressants such as amitriptyline are a first-line treatment for chronic pain conditions, indicating ... -
Commonly prescribed anti-depressants: What clinicians need to know
(The Psychological Society of Ireland (PSI), 2011-10)According to two Cochrane collaboration reviews (Moncrieff, Wessely, & Hardy, 2004; Turner, Mathews, Linardatos, Tell, & Rosenthal, 2008), the efficacy of modern antidepressants has yet to be conclusively demonstrated ... -
Development and characterisation of a novel preclinical test battery for detecting anxiolytic and antidepressant properties of drugs
(2016-10-19)Depression is a chronic, recurring and potentially life-threatening disorder that is highly comorbid with anxiety. The aetiology of depression, anxiety and their comorbidity is still largely unknown. Despite the development ... -
Modelling early life exposure to antidepressants in rats: Developmental, behavioural and neurochemical aspects
(2013-02-11)Depression during pregnancy and the postpartum period has been associated with deleterious consequences such as preterm birth, low birth weight and less optimal scores on neonatal reflexes and behaviour. Pharmacological ...