Browsing by Subject "bcl-2 family"
Now showing items 1-3 of 3
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Deficiency in the mitochondrial apoptotic pathway reveals the toxic potential of autophagy under er stress conditions
(Informa UK Limited, 2014-11-02)Endoplasmic reticulum (ER) stress-induced cell death is normally associated with activation of the mitochondrial apoptotic pathway, which is characterized by CYCS (cytochrome c, somatic) release, apoptosome formation, and ... -
Disruption of microrna biogenesis confers resistance to er stress-induced cell death upstream of the mitochondrion
(Public Library of Science (PLoS), 2013-08-19)Global downregulation of microRNAs (miRNAs) is a common feature of human tumors and has been shown to enhance cancer progression. Several components of the miRNA biogenesis machinery (XPO5, DICER and TRBP) have been shown ... -
Heat shock preconditioning protects against er stress-induced apoptosis through the regulation of the bh3-only protein bim
(Wiley-Blackwell, 2014-01-01)