Browsing by Subject "anaphase"
Now showing items 1-2 of 2
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Analysis of scc1-deficient cells defines a key metaphase role of vertebrate cohesin in linking sister kinetochores
(Wiley-Blackwell, 2004-02-01)Cleavage of the cohesin subunit Scc1p/Mcd1p/Rad21 permits sister chromatid separation and is considered to trigger anaphase onset. It has also been suggested that the cohesin complex is essential for chromosome condensation ... -
Sister chromatid cohesion and genome stability in vertebrate cells
(Portland Press Ltd., 2003-02-01)For successful eukaryotic mitosis, sister chromatid pairs remain linked after replication until their kinetochores have been attached to opposite spindle poles by microtubules. This linkage is broken at the metaphase-anaphase ...