Browsing by Subject "analogs"
Now showing items 1-12 of 12
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Comparative effects of the marine algal toxins azaspiracid-1, -2, and -3 on jurkat t lymphocyte cells
(American Chemical Society (ACS), 2012-03-19)Azaspiracids (AZA) are polyether marine toxins of dinoflagellate origin that accumulate in shellfish and represent an emerging human health risk. Although monitored and regulated in many European and Asian countries, there ... -
Effects of heating on proportions of azaspiracids 1–10 in mussels (mytilus edulis) and identification of carboxylated precursors for azaspiracids 5, 10, 13, and 15
(American Chemical Society (ACS), 2015-12-30)Azaspiracids (AZAs) are marine biotoxins that induce human illness following the consumption of contaminated shellfish. European Union regulation stipulates that only raw shellfish are tested, yet shellfish are often cooked ... -
Formation of azaspiracids-3, -4, -6, and -9 via decarboxylation of carboxyazaspiracid metabolites from shellfish
(American Chemical Society (ACS), 2009-01-14)The azaspiracid (AZA) class of phycotoxins has been responsible for extended closures of shellfisheries in various locations around Europe, where levels of AZA1-3 are regulated in shellfish. Since their discovery in 1995, ... -
Improved isolation procedure for azaspiracids from shellfish, structural elucidation of azaspiracid-6, and stability studies
(American Chemical Society (ACS), 2012-03-14)Azaspiracids are a group of lipophilic polyether toxins produced by the small dinoflagellate Azadinium spinosum. They may accumulate in shellfish and can result in illnesses when consumed by humans. Research into analytical ... -
Isolation, structure elucidation, relative lc-ms response, and in vitro toxicity of azaspiracids from the dinoflagellateazadinium spinosum
(American Chemical Society (ACS), 2014-11-26)We identified three new azaspiracids (AZAs) with molecular weights of 715, 815, and 829 (AZA33 (3), AZA34 (4), and AZA35, respectively) in mussels, seawater, and Azadinium spinosum culture. Approximately 700 mu g of 3 and ... -
Quantitative analysis of azaspiracids in azadinium spinosum cultures
(Springer Nature, 2012-02-26)Azaspiracids (AZAs) are secondary metabolites of Azadinium spinosum that can accumulate in shellfish and cause food poisoning when consumed. We describe here an analytical procedure for the determination of AZAs in cultures ... -
Structural characterization of the lipid a component of helicobacter pylori rough- and smooth-form lipopolysaccharides.
(American Society for Microbiology, 1997-10-01)The chemical structure of free lipid A isolated from rough-and smooth-form lipopolysaccharides (R-LPS and S-LPS, respectively) of the human gastroduodenal pathogen Helicobacter pylori was elucidated by compositional and ... -
Structure elucidation, relative lc–ms response and in vitro toxicity of azaspiracids7–10isolated from mussels (mytilus edulis)
(American Chemical Society (ACS), 2015-05-27)Azaspiracids (AZAs) are marine biotoxins produced by dinoflagellates that can accumulate in shellfish, which if consumed can lead to poisoning events. AZA7-10, 7-10, were isolated from shellfish and their structures, ... -
Synthesis of a-o- and a-s-glycosphingolipids related to sphingomonous cell wall antigens using anomerisation
(MDPI AG, 2013-09-12)Analogues of glycolipids from Spingomonadacaece with O- and S- and SO2-linkages have been prepared using chelation induced anomerisation promoted by TiCl4. Included are examples of the anomerisation of intermediates with ... -
The preparation of certified calibration solutions for azaspiracid-1, -2, and -3, potent marine biotoxins found in shellfish
(Springer Nature, 2010-09-09)The production and certification of a series of azaspiracid (AZA) calibration solution reference materials is described. Azaspiracids were isolated from contaminated mussels, purified by preparative liquid chromatography ... -
The role of azadinium spinosum (dinophyceae) in the production of azaspiracid shellfish poisoning in mussels
(Elsevier BV, 2011-09-01)