Now showing items 1-2 of 2

    • Amorphous pharmaceuticals and composites 

      Gniado, Katarzyna (NUI Galway, 2018-04-27)
      An attractive, yet challenging approach to overcome poor water solubility is to convert a crystalline Active Pharmaceutical Ingredient (API) into its more soluble amorphous form.1-3 Nevertheless, the use of amorphous drug ...
    • Investigation of the capacity of low glass transition temperature excipients to minimize amorphization of sulfadimidine on comilling 

      Curtin, Vincent; Amharar, Youness; Hu, Yun; Erxleben, Andrea; McArdle, Patrick; Caron, Vincent; Tajber, Lidia; Corrigan, Owen I.; Healy, Anne Marie (American Chemical Society (ACS), 2013-01-07)
      The coprocessing of active pharmaceutical ingredient (API) with an excipient which has a high glass transition temperature (T-g) is a recognized strategy to stabilize the amorphous form of a drug. This work investigates ...