Browsing by Subject "amorphous"
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Amorphous pharmaceuticals and composites
(NUI Galway, 2018-04-27)An attractive, yet challenging approach to overcome poor water solubility is to convert a crystalline Active Pharmaceutical Ingredient (API) into its more soluble amorphous form.1-3 Nevertheless, the use of amorphous drug ... -
Investigation of the capacity of low glass transition temperature excipients to minimize amorphization of sulfadimidine on comilling
(American Chemical Society (ACS), 2013-01-07)The coprocessing of active pharmaceutical ingredient (API) with an excipient which has a high glass transition temperature (T-g) is a recognized strategy to stabilize the amorphous form of a drug. This work investigates ...