Browsing by Subject "Biomarkers"
Now showing items 1-7 of 7
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Analysis of MiRNA Expression and Biomarker Potential in Common Diseases: Breast Cancer and Obesity
(2012-05-28)The two greatest health concerns worldwide at present are cancer and obesity; both of which continue to rise in incidence and are associated with high morbidity and mortality. Understanding the aetiology and mechanisms of ... -
Cross platform standardisation of an experimental pipeline for use in the identification of dysregulated human circulating MiRNAs
(Public Library of Science, 2015-09-10)Micro RNAs (miRNAs) are a class of highly conserved small non-coding RNAs that play an important part in the post-transcriptional regulation of gene expression. A substantial number of miRNAs have been proposed as biomarkers ... -
DNA Immobilization and Detection on Cellulose Paper using a Surface Grown Cationic Polymer via ATRP
(American Chemical Society, 2012-02-02)Cationic polymers with various structures have been widely investigated in the areas of medical diagnostics and molecular, biology because of their unique binding properties and capability to interact with biological ... -
MiRNAs as oncologic biomarkers for breast cancer
(2014-08-18)Understanding of the molecular complexity underlying breast cancer has greatly advanced in recent years. Distinct phenotypic subtypes have been identified each of which carry prognostic and predictive implications. Despite ... -
Potential biomarkers of acute ischemic stroke etiology revealed by mass spectrometry based proteomic characterization of formalin-fixed paraffin-embedded blood clots
(Frontiers Media, 2022-04-19)Background and Aims: Besides the crucial role in the treatment of acute ischemic stroke (AIS), mechanical thrombectomy represents a unique opportunity for researchers to study the retrieved clots, with the possibility of ... -
The role of novel biomarkers in addressing the burden of chronic kidney disease in diabetes mellitus
(NUI Galway, 2022-10-06)Kidney disease due to diabetes (Diabetic Kidney Disease (DKD)) is the leading cause of chronic kidney disease worldwide. It is an underappreciated, often under-recognised component of the overall burden of diabetes. People ... -
Towards precision medicine: discovering novel gynecological cancer biomarkers and pathways using linked data
(BioMed Central, 2017-09-19)Next Generation Sequencing (NGS) is playing a key role in therapeutic decision making for the cancer prognosis and treatment. The NGS technologies are producing a massive amount of sequencing datasets. Often, these datasets ...