Now showing items 1-2 of 2

    • Genome-wide autozygosity is associated with lower general cognitive ability 

      Howrigan, D P; Simonson, M A; Davies, G; Harris, S E; Tenesa, A; Starr, J M; Liewald, D C; Deary, I J; McRae, A; Wright, M J; Montgomery, G W; Hansell, N; Martin, N G; Payton, A; Horan, M; Ollier, W E; Abdellaoui, A; Boomsma, D I; DeRosse, P; Knowles, E E M; Glahn, D C; Djurovic, S; Melle, I; Andreassen, O A; Christoforou, A; Steen, V M; Hellard, S L; Sundet, K; Reinvang, I; Espeseth, T; Lundervold, A J; Giegling, I; Konte, B; Hartmann, A M; Rujescu, D; Roussos, P; Giakoumaki, S; Burdick, K E; Bitsios, P; Donohoe, G; Corley, R P; Visscher, P M; Pendleton, N; Malhotra, A K; Neale, B M; Lencz, T; Keller, M C (Springer Nature, 2015-09-22)
      Inbreeding depression refers to lower fitness among offspring of genetic relatives. This reduced fitness is caused by the inheritance of two identical chromosomal segments (autozygosity) across the genome, which may expose ...
    • Gwas meta-analysis reveals novel loci and genetic correlates for general cognitive function: a report from the cogent consortium 

      Trampush, J W; Yang, M L Z; Yu, J; Knowles, E; Davies, G; Liewald, D C; Starr, J M; Djurovic, S; Melle, I; Sundet, K; Christoforou, A; Reinvang, I; DeRosse, P; Lundervold, A J; Steen, V M; Espeseth, T; Räikkönen, K; Widen, E; Palotie, A; Eriksson, J G; Giegling, I; Konte, B; Roussos, P; Giakoumaki, S; Burdick, K E; Payton, A; Ollier, W; Horan, M; Chiba-Falek, O; Attix, D K; Need, A C; Cirulli, E T; Voineskos, A N; Stefanis, N C; Avramopoulos, D; Hatzimanolis, A; Arking, D E; Smyrnis, N; Bilder, R M; Freimer, N A; Cannon, T D; London, E; Poldrack, R A; Sabb, F W; Congdon, E; Conley, E D; Scult, M A; Dickinson, D; Straub, R E; Donohoe, G; Morris, Derek W.; Corvin, A; Gill, M; Hariri, A R; Weinberger, D R; Pendleton, N; Bitsios, P; Rujescu, D; Lahti, J; Le Hellard, S; Keller, M C; Andreassen, O A; Deary, I J; Glahn, D C; Malhotra, A K; Lencz, T (Springer Nature, 2017-01-17)
      The complex nature of human cognition has resulted in cognitive genomics lagging behind many other fields in terms of gene discovery using genome-wide association study (GWAS) methods. In an attempt to overcome these ...