Now showing items 1-2 of 2

    • N-wasp is a novel regulator of hair-follicle cycling that controls antiproliferative tgf  pathways 

      Lefever, T.; Pedersen, E.; Basse, A.; Paus, R.; Quondamatteo, F.; Stanley, A. C.; Langbein, L.; Wu, X.; Wehland, J.; Lommel, S.; Brakebusch, C. (The Company of Biologists, 2009-12-16)
      N-WASP is a cytoplasmic molecule mediating Arp2/3 nucleated actin polymerization. Mice with a keratinocyte-specific deletion of the gene encoding N-WASP showed normal interfollicular epidermis, but delayed hair-follicle ...
    • Rhoa is dispensable for skin development, but crucial for contraction and directed migration of keratinocytes 

      Jackson, B.; Peyrollier, K.; Pedersen, E.; Basse, A.; Karlsson, R.; Wang, Z.; Lefever, T.; Ochsenbein, A. M.; Schmidt, G.; Aktories, K.; Stanley, A.; Quondamatteo, F.; Ladwein, M.; Rottner, K.; van Hengel, J.; Brakebusch, C. (American Society for Cell Biology (ASCB), 2011-01-05)
      RhoA is a small guanosine-5'-triphosphatase (GTPase) suggested to be essential for cytokinesis, stress fiber formation, and epithelial cell-cell contacts. In skin, loss of RhoA was suggested to underlie pemphigus skin ...